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Safety and efficacy of endoscopic submucosal dissection for superficial esophageal cancer with esophageal varices.
Nakai, Tatsuya; Yoshizaki, Tetsuya; Tanaka, Shinwa; Yamamoto, Yoshinobu; Sako, Tomoya; Kitamura, Yasuaki; Ose, Takayuki; Ishida, Tsukasa; Ikeda, Atsushi; Ariyoshi, Ryusuke; Iwatate, Mineo; Kawara, Fumiaki; Takao, Toshitatsu; Morita, Yoshinori; Toyonaga, Takashi; Kodama, Yuzo.
Afiliación
  • Nakai T; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki­cho, Chuo­ku, Kobe, Hyogo, 650­0017, Japan.
  • Yoshizaki T; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki­cho, Chuo­ku, Kobe, Hyogo, 650­0017, Japan. yoshizak@med.kobe-u.ac.jp.
  • Tanaka S; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki­cho, Chuo­ku, Kobe, Hyogo, 650­0017, Japan.
  • Yamamoto Y; Department of Gastroenterological Oncology, Hyogo Cancer Center, Akashi, Japan.
  • Sako T; Department of Gastroenterology, Osaka Saiseikai Nakatsu Hospital, Osaka, Japan.
  • Kitamura Y; Department of Gastroenterology, Yodogawa Christian Hospital, Osaka, Japan.
  • Ose T; Department of Gastroenterology, Kita-Harima Medical Center, Ono, Japan.
  • Ishida T; Department of Gastroenterology, Akashi Medical Center, Akashi, Japan.
  • Ikeda A; Department of Gastroenterology, Sanda City Hospital, Sanda, Japan.
  • Ariyoshi R; Department of Gastroenterology, Steel Memorial Hirohata Hospital, Himeji, Japan.
  • Iwatate M; Department of Gastroenterology, Sano Hospital, Kobe, Japan.
  • Kawara F; Department of Gastroenterology, Konan Medical Center, Kobe, Japan.
  • Takao T; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki­cho, Chuo­ku, Kobe, Hyogo, 650­0017, Japan.
  • Morita Y; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki­cho, Chuo­ku, Kobe, Hyogo, 650­0017, Japan.
  • Toyonaga T; Department of Endoscopy, Kobe University Hospital, Kobe, Japan.
  • Kodama Y; Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki­cho, Chuo­ku, Kobe, Hyogo, 650­0017, Japan.
Esophagus ; 20(3): 515-523, 2023 07.
Article en En | MEDLINE | ID: mdl-37060531
BACKGROUND: Heavy drinking is associated with esophageal cancer and esophageal varices. However, there are limited reports of endoscopic resection for esophageal cancer with esophageal varices. In this multicenter study, we clarified the safety and efficacy of endoscopic submucosal dissection for superficial esophageal cancer with esophageal varices. METHODS: In this multicenter, retrospective, observational study, patients underwent esophageal endoscopic submucosal dissection at 10 referral centers in Japan from January 2013 to December 2019. We analyzed characteristics including backgrounds and varices, treatment outcomes, and adverse events in cases with esophageal varices. RESULTS: A total of 1708 patients were evaluated, 27 (1.6%) of whom had esophageal varices. In patients with esophageal varices, the en bloc resection rate and R0 resection rate were 100% and 77.8%, respectively. Patients with esophageal varices had longer procedure times than patients without esophageal varices (p = 0.015). There was no significant difference in adverse events. There was no significant difference in procedure time and number of adverse events between patients who underwent pretreatment and those who did not. There was no significant difference in these outcomes for patients with lesions on varices compared to those without. Child-Pugh classification and location of the lesions also did not affect these outcomes. CONCLUSIONS: Esophageal cancer with esophageal varices could be treated endoscopically safely and effectively.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Várices / Neoplasias Esofágicas / Várices Esofágicas y Gástricas / Resección Endoscópica de la Mucosa Tipo de estudio: Clinical_trials / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Esophagus Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Várices / Neoplasias Esofágicas / Várices Esofágicas y Gástricas / Resección Endoscópica de la Mucosa Tipo de estudio: Clinical_trials / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Esophagus Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Japón