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Evaluation of non-exudative tomographic signs in cases of exudative age-related macular degeneration.
Monje-Fernández, L; Gallego-Pinazo, R; Cordero-Coma, M; Donate-López, J; Coco-Martín, R M; Dolz-Marco, R.
Afiliación
  • Monje-Fernández L; Complejo Asistencial Universitario de León, León, Spain. Electronic address: lmonje@saludcastillayleon.es.
  • Gallego-Pinazo R; Unidad de Mácula, Clínica Oftalvist Valencia, Valencia, Spain.
  • Cordero-Coma M; Área de Oftalmología, HM Hospitales, Málaga, Spain.
  • Donate-López J; Clínica la Luz, Madrid, Spain.
  • Coco-Martín RM; Instituto de Oftalmo Biología Aplicada (IOBA), Valladolid, Spain.
  • Dolz-Marco R; Unidad de Mácula, Clínica Oftalvist Valencia, Valencia, Spain.
Arch Soc Esp Oftalmol (Engl Ed) ; 98(5): 276-280, 2023 May.
Article en En | MEDLINE | ID: mdl-37037324
OBJECTIVE: To analyse the prevalence of non-exudative tomographic signs (onion sign, pseudoswelling, external retinal tubulation, pseudocysts, subretinal clefts and macular atrophy) in patients with neovascular age-related macular degeneration. MATERIAL AND METHODS: A total of 174 eyes of patients with neovascular age-related macular degeneration who had not received previous treatment were included in the study. Visual acuity, neovascularization activity, and the appearance or not of the different signs under study were assessed at times 0 (initial visit), 4 months, one year, year and a half, and at 2 and 3 years of follow-up. The following were also evaluated: age, sex, affected eye and type of neovascularization (1, 2, 3, polypoid or mixed). The analysis were performed using the statistical software R (version 3.3.2) and the glmmADMB package (version 0.8.3.3). RESULTS: The presence of pseudocysts and external retinal tubulation increases throughout the follow-up. The onion sign begins with an ascending frequency up to 12 months, then decreases at 18 months and increases again at 24 months. Regarding pseudowelling, it maintains an increase until 18 months to finally decrease. Subretinal clefts is the rarest sign, presenting in 1.1% on the first visit. Finally, macular atrophy, present in 12.6% of the eyes initially, is found in 25% after 2 years. CONCLUSION: Pseudocysts, external retinal tubulation and macular atrophy were the most prevalent signs, while subretinal clefts were the most infrequent.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tomografía de Coherencia Óptica / Degeneración Macular Tipo de estudio: Diagnostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Arch Soc Esp Oftalmol (Engl Ed) Año: 2023 Tipo del documento: Article Pais de publicación: España
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tomografía de Coherencia Óptica / Degeneración Macular Tipo de estudio: Diagnostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Arch Soc Esp Oftalmol (Engl Ed) Año: 2023 Tipo del documento: Article Pais de publicación: España