Orexin A, an amphipathic &#945;-helical neuropeptide involved in pleiotropic functions in the nervous and immune systems: Synthetic approach and biophysical studies of the membrane-bound state.

Ball, Haydn L; Said, Hooda; Chapman, Karen; Fu, Riqiang; Xiong, Yawei; Burk, Joshua A; Rosenbaum, Daniel; Veneziano, Remi; Cotten, Myriam L

Orexin A, an amphipathic α-helical neuropeptide involved in pleiotropic functions in the nervous and immune systems: Synthetic approach and biophysical studies of the membrane-bound state.

Ball, Haydn L; Said, Hooda; Chapman, Karen; Fu, Riqiang; Xiong, Yawei; Burk, Joshua A; Rosenbaum, Daniel; Veneziano, Remi; Cotten, Myriam L.

Afiliación

Ball HL; Department of Chemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Said H; Department of Bioengineering, College of Engineering and Computing, George Mason University, Fairfax, VA 22030, USA.
Chapman K; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Fu R; National High Magnetic Field Laboratory, Tallahassee, FL 32310, USA.
Xiong Y; Department of Applied Science, William & Mary, Williamsburg, VA 23185, USA.
Burk JA; Department of Psychological Sciences, William & Mary, Williamsburg, VA 23185, USA.
Rosenbaum D; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Veneziano R; Department of Bioengineering, College of Engineering and Computing, George Mason University, Fairfax, VA 22030, USA.
Cotten ML; Department of Applied Science, William & Mary, Williamsburg, VA 23185, USA. Electronic address: mcotten@wm.edu.

Biophys Chem ; 297: 107007, 2023 06.

Article en En | MEDLINE | ID: mdl-37037119

Asunto(s)

Neuropéptidos; Orexinas; Secuencia de Aminoácidos; Neuropéptidos/química; Neuropéptidos/fisiología; Péptidos/química; Fosfolípidos; Sistema Inmunológico; Dicroismo Circular

Palabras clave

Anti-inflammatory; Circular dichroism; Hypocretin; Isotopic labeling; Membrane interactions; Neuropeptide; Nuclear magnetic resonance (NMR); Orexin; Receptor activation; Surface plasmon resonance; Synthesis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neuropéptidos Idioma: En Revista: Biophys Chem Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos

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