Relaxin-encapsulated polymeric metformin nanoparticles remodel tumor immune microenvironment by reducing CAFs for efficient triple-negative breast cancer immunotherapy.

Zhang, Hongyan; Chen, Liying; Zhao, Yue; Luo, Ningchao; Shi, Jingbin; Xu, Shujun; Ma, Lisha; Wang, Menglin; Gu, Mancang; Mu, Chaofeng; Xiong, Yang

Zhang, Hongyan; Chen, Liying; Zhao, Yue; Luo, Ningchao; Shi, Jingbin; Xu, Shujun; Ma, Lisha; Wang, Menglin; Gu, Mancang; Mu, Chaofeng; Xiong, Yang.

Afiliación

Zhang H; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Chen L; Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Zhao Y; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Luo N; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Shi J; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Xu S; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Ma L; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Wang M; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Gu M; Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, NC 27599, United States.
Mu C; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.
Xiong Y; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China.

Asian J Pharm Sci ; 18(2): 100796, 2023 Mar.

Article en En | MEDLINE | ID: mdl-37008735

Palabras clave

Cancer-associated fibroblasts; Lipid nanoparticles; PD-L1 antibody; Plasmid encoding relaxin; Polymeric metformin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Asian J Pharm Sci Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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