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Measuring Oxygen Consumption Rate (OCR) and Extracellular Acidification Rate (ECAR) in Muscle Stem Cells Using a Seahorse Analyzer: Applicability for Aging Studies.
Hong, Xiaotong; Muñoz-Cánoves, Pura.
Afiliación
  • Hong X; Spanish National Center on Cardiovascular Research (CNIC), Madrid, Spain.
  • Muñoz-Cánoves P; Altos Labs Inc, San Diego, CA, USA.
Methods Mol Biol ; 2640: 73-88, 2023.
Article en En | MEDLINE | ID: mdl-36995588
In recent years, evidence showing metabolism as a fundamental regulator of stem cell functions has emerged. In skeletal muscle, its stem cells (satellite cells) sustain muscle regeneration, although they lose their regenerative potential with aging, and this has been attributed, at least in part, to changes in their metabolism. In this chapter, we describe a protocol to analyze the metabolism of satellite cells using the Seahorse technology, which can be applied to aging mice.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Smegmamorpha Límite: Animals Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Smegmamorpha Límite: Animals Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos