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[Analysis of anti-SARS-CoV-2 IgG antibody titers after mRNA booster vaccination in patients with nonmalignant hematological disorders].
Hagihara, Masao; Sugi, Tomiyuki; Hayashi, Hiroyoshi; Nakashima, Shiori; Ohara, Shin; Imai, Yui; Nakano, Hirofumi; Uchida, Tomoyuki; Inoue, Morihiro; Mitamura, Keiko.
Afiliación
  • Hagihara M; Department of Hematology, Eiju General Hospital.
  • Sugi T; Department of Pharmacy, Eiju General Hospital.
  • Hayashi H; Department of Hematology, Eiju General Hospital.
  • Nakashima S; Department of Hematology, Eiju General Hospital.
  • Ohara S; Department of Hematology, Eiju General Hospital.
  • Imai Y; Department of Hematology, Eiju General Hospital.
  • Nakano H; Department of Hematology, Eiju General Hospital.
  • Uchida T; Department of Hematology, Eiju General Hospital.
  • Inoue M; Department of Hematology, Eiju General Hospital.
  • Mitamura K; Department of Preventive Medicine, Eiju General Hospital.
Rinsho Ketsueki ; 64(2): 133-136, 2023.
Article en Ja | MEDLINE | ID: mdl-36990734
In our facility, anti-SARS-CoV-2 mRNA vaccines were given to 21 patients, including 8 with aplastic anemia (AA), 3 with pure red cell aplasia (PRCA), and 10 with immune thrombocytopenic purpura (ITP), and IgG antibody titers were assessed one month after vaccinations. After receiving both a second vaccine and a booster shot, all patients with AA/PRCA treated with cyclosporine A aside from one, had IgG titers that were lower than the median levels of healthy controls. Even if prednisolone (PSL) doses did not go over 10 mg/day, ITP patients receiving PSL therapy were unable to achieve adequate levels of IgG after booster immunizations.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Púrpura Trombocitopénica Idiopática / Aplasia Pura de Células Rojas / COVID-19 / Enfermedades Hematológicas / Anemia Aplásica Límite: Humans Idioma: Ja Revista: Rinsho Ketsueki Año: 2023 Tipo del documento: Article Pais de publicación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Púrpura Trombocitopénica Idiopática / Aplasia Pura de Células Rojas / COVID-19 / Enfermedades Hematológicas / Anemia Aplásica Límite: Humans Idioma: Ja Revista: Rinsho Ketsueki Año: 2023 Tipo del documento: Article Pais de publicación: Japón