Your browser doesn't support javascript.
loading
Probiotic intervention benefits multiple neural behaviors in older adults with mild cognitive impairment.
Fei, Yuzhe; Wang, Ruiru; Lu, Jiachun; Peng, Songhao; Yang, Song; Wang, Yiting; Zheng, Kaixuan; Li, Ran; Lin, Lin; Li, Maoquan.
Afiliación
  • Fei Y; School of Public Health, Chengdu Medical College, Chengdu, Sichuan, PR China.
  • Wang R; School of Public Health, Chengdu Medical College, Chengdu, Sichuan, PR China.
  • Lu J; Chengdu Eighth People's Hospital, Chengdu, Sichuan, PR China.
  • Peng S; Chengdu Eighth People's Hospital, Chengdu, Sichuan, PR China.
  • Yang S; School of Public Health, Chengdu Medical College, Chengdu, Sichuan, PR China.
  • Wang Y; School of Public Health, Chengdu Medical College, Chengdu, Sichuan, PR China.
  • Zheng K; Chengdu Qingbaijiang District Traditional Chinese Medicine Hospital, Chengdu, Sichuan, PR China.
  • Li R; School of Public Health, Chengdu Medical College, Chengdu, Sichuan, PR China.
  • Lin L; Sichuan Collaborative Innovation Center for Elderly Care and Health, Chengdu, Sichuan, PR China; Geriatric Health Academy, Chengdu Medical College, Chengdu, Sichuan, PR China; Chengdu Eighth People's Hospital, Chengdu, Sichuan, PR China. Electronic address: 617866353@qq.com.
  • Li M; School of Public Health, Chengdu Medical College, Chengdu, Sichuan, PR China; Sichuan Collaborative Innovation Center for Elderly Care and Health, Chengdu, Sichuan, PR China; Chengdu Qingbaijiang District Traditional Chinese Medicine Hospital, Chengdu, Sichuan, PR China. Electronic address: limquan@
Geriatr Nurs ; 51: 167-175, 2023.
Article en En | MEDLINE | ID: mdl-36990042
Probiotic supplements were shown to improve cognitive function in Alzheimer's disease (AD) patients. However, it is still unclear whether this applies to older individuals with mild cognitive impairment (MCI). We aimed to explore the effects of probiotic supplementation on multiple neural behaviors in older adults with MCI. Forty-two MCI patients (age > 60 years) were randomly divided into two groups and consumed either probiotics (n=21) or placebo (n=21) for 12 weeks. Various scale scores, gut microbiota measures and serological indicators were recorded pre- and posttreatment. After 12 weeks of intervention, cognitive function and sleep quality were improved in the probiotic group compared with those in the control group, and the underlying mechanisms were associated with changes in the intestinal microbiota. In conclusion, our study demonstrated that probiotic treatment enhanced cognitive function and sleep quality in older MCI patients, thus providing important insights into the clinical prevention and treatment of MCI.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Probióticos / Enfermedad de Alzheimer / Disfunción Cognitiva Tipo de estudio: Clinical_trials Límite: Aged / Humans Idioma: En Revista: Geriatr Nurs Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Probióticos / Enfermedad de Alzheimer / Disfunción Cognitiva Tipo de estudio: Clinical_trials Límite: Aged / Humans Idioma: En Revista: Geriatr Nurs Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos