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Dissemination of Clinical Acinetobacter baumannii Isolate to Hospital Environment during the COVID-19 Pandemic.
Pustijanac, Emina; Hrenovic, Jasna; Vranic-Ladavac, Mirna; Mocenic, Martina; Karcic, Natalie; Lazaric Stefanovic, Lorena; Hrstic, Irena; Loncaric, Jasenka; Seruga Music, Martina; Drcelic, Marina; Majstorovic, Dijana; Kovacic, Ines.
Afiliación
  • Pustijanac E; Faculty of Natural Sciences, Juraj Dobrila University of Pula, 52100 Pula, Croatia.
  • Hrenovic J; Department of Biology, Faculty of Science, University of Zagreb, 10000 Zagreb, Croatia.
  • Vranic-Ladavac M; Public Health Institute of Istria County, 52100 Pula, Croatia.
  • Mocenic M; General Hospital Pula, 52100 Pula, Croatia.
  • Karcic N; Public Health Institute of Istria County, 52100 Pula, Croatia.
  • Lazaric Stefanovic L; General Hospital Pula, 52100 Pula, Croatia.
  • Hrstic I; General Hospital Pula, 52100 Pula, Croatia.
  • Loncaric J; General Hospital Pula, 52100 Pula, Croatia.
  • Seruga Music M; Department of Biology, Faculty of Science, University of Zagreb, 10000 Zagreb, Croatia.
  • Drcelic M; Department of Biology, Faculty of Science, University of Zagreb, 10000 Zagreb, Croatia.
  • Majstorovic D; Faculty of Medicine, Juraj Dobrila University of Pula, 52100 Pula, Croatia.
  • Kovacic I; Faculty of Educational Sciences, Juraj Dobrila University of Pula, 52100 Pula, Croatia.
Pathogens ; 12(3)2023 Mar 03.
Article en En | MEDLINE | ID: mdl-36986332
The aim of this study was to find the source of Acinetobacter baumannii in the intensive care unit (ICU) after an outbreak during the coronavirus disease 2019 (COVID-19) pandemic, as there was no A. baumannii detected on usually screened susceptible surfaces. The screening of the ICU environment was done in April 2021 when eleven different samples were taken. One A. baumannii isolate was recovered from the air conditioner and was compared with four clinical A. baumannii isolates obtained from patients hospitalized in January 2021. Isolates were confirmed by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), minimum inhibitory concentrations (MICs) were determined, and the multilocus sequence typing (MLST) was performed. The molecular identification of A. baumannii isolates as ST208, the presence of the same blaOXA-23 carbapenemase gene, and the same antibiotic susceptibility profile suggest that the isolate recovered from the air conditioner is the same as the isolates recovered from hospitalized patients. The environmental isolate was recovered three months later than the clinical isolates, emphasizing the ability of A. baumannii to survive on dry abiotic surfaces. The air conditioner in the clinical environment is an important but undoubtedly neglected source of A. baumannii outbreaks, hence, frequent disinfection of hospital air conditioners with appropriate disinfectants is mandatory to mitigate the circulation of A. baumannii between patients and the hospital environment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pathogens Año: 2023 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pathogens Año: 2023 Tipo del documento: Article País de afiliación: Croacia Pais de publicación: Suiza