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Severe Course of COVID-19 and Long-COVID-19 in Children: Difficulties in Diagnosis.
Vasichkina, Elena; Kofeynikova, Olga; Fetisova, Svetlana; Starshinova, Anastasia Y; Sheyanova, Elizaveta; Vershinina, Tatiana; Ryzhkov, Anton; Skripnik, Aleksey; Alekseeva, Daria; Nechaeva, Elizaveta; Glushkova, Anzhela; Kudlay, Dmitry; Pervunina, Tatiana; Starshinova, Anna.
Afiliación
  • Vasichkina E; Almazov National Medical Research Centre, St. Petersburg 197341, Russia.
  • Kofeynikova O; Almazov National Medical Research Centre, St. Petersburg 197341, Russia.
  • Fetisova S; Almazov National Medical Research Centre, St. Petersburg 197341, Russia.
  • Starshinova AY; Medical Department, Saint Petersburg State Pediatric Medical University, St. Petersburg 194100, Russia.
  • Sheyanova E; Almazov National Medical Research Centre, St. Petersburg 197341, Russia.
  • Vershinina T; Almazov National Medical Research Centre, St. Petersburg 197341, Russia.
  • Ryzhkov A; Almazov National Medical Research Centre, St. Petersburg 197341, Russia.
  • Skripnik A; Almazov National Medical Research Centre, St. Petersburg 197341, Russia.
  • Alekseeva D; Almazov National Medical Research Centre, St. Petersburg 197341, Russia.
  • Nechaeva E; H.Turner National Medical Research Center for Children's Orthopedics and Trauma Surgery, St. Petersburg 196603, Russia.
  • Glushkova A; Almazov National Medical Research Centre, St. Petersburg 197341, Russia.
  • Kudlay D; V.M. Bekhterev National Research Medical Center for Psychiatry and Neurology, St. Petersburg 192019, Russia.
  • Pervunina T; Pharmacology Department, I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Moscow 119435, Russia.
  • Starshinova A; SSC Immunology Institute, FMBA Russia, Moscow 115552, Russia.
Life (Basel) ; 13(3)2023 Mar 14.
Article en En | MEDLINE | ID: mdl-36983936
The question of COVID-19 and long-COVID-19 course in children remains unsolved. This infection in children, which is associated with COVID-19, can vary from asymptomatic to systemic damage of various systems. Multisystem inflammatory syndrome in children, associated with SARS-CoV-2 (MIS-C), is a serious condition in children and adolescents after experiencing COVID-19. Published data on MIS-C have indicated that the inflammation can be registered in the gastrointestinal tract (60-100%), as well as in cardiovascular (80%), nervous (29-58%), and respiratory (21-65%) systems. However, with the changing characteristics of SARS-CoV-2, the manifestations of COVID-19 and long-COVID-19 in children have also been changing. Currently, there is no clear understanding of the development of severe COVID-19 and MIS-C in children, especially after being exposed to patients with COVID-19. We presented two new clinical courses of multisystem inflammatory syndrome in children with severe multisystem damage after close contact to relatives with COVID-19 or long-COVID-19. Thus, high-risk children, who are positive for SARS-CoV-2 infection after contact with COVID-19 patients, should be clinically managed during the first few months. The identification of the disease complexity requires the involvement of neurologists, cardiologists, and other specialists.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Life (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Life (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: Suiza