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Ganglioglioma with adverse clinical outcome and atypical histopathological features were defined by alterations in PTPN11/KRAS/NF1 and other RAS-/MAP-Kinase pathway genes.
Hoffmann, Lucas; Coras, Roland; Kobow, Katja; López-Rivera, Javier A; Lal, Dennis; Leu, Costin; Najm, Imad; Nürnberg, Peter; Herms, Jochen; Harter, Patrick N; Bien, Christian G; Kalbhenn, Thilo; Müller, Markus; Pieper, Tom; Hartlieb, Till; Kudernatsch, Manfred; Hamer, Hajo; Brandner, Sebastian; Rössler, Karl; Blümcke, Ingmar; Jabari, Samir.
Afiliación
  • Hoffmann L; Department of Neuropathology, Partner of the European Reference Network (ERN) EpiCARE, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, 91054, Germany.
  • Coras R; Department of Neuropathology, Partner of the European Reference Network (ERN) EpiCARE, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, 91054, Germany.
  • Kobow K; Department of Neuropathology, Partner of the European Reference Network (ERN) EpiCARE, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, 91054, Germany.
  • López-Rivera JA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, USA.
  • Lal D; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
  • Leu C; Charles Shor Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, USA.
  • Najm I; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
  • Nürnberg P; Charles Shor Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, USA.
  • Herms J; Stanley Center for Psychiatric Research, Broad Institute of Harvard and M.I.T, Cambridge, MA, 02142, USA.
  • Harter PN; Cologne Center for Genomics (CCG), Medical Faculty of the University of Cologne, University Hospital of Cologne, 50931, Cologne, Germany.
  • Bien CG; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
  • Kalbhenn T; Charles Shor Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, USA.
  • Müller M; Stanley Center for Psychiatric Research, Broad Institute of Harvard and M.I.T, Cambridge, MA, 02142, USA.
  • Pieper T; Cologne Center for Genomics (CCG), Medical Faculty of the University of Cologne, University Hospital of Cologne, 50931, Cologne, Germany.
  • Hartlieb T; Charles Shor Epilepsy Center, Neurological Institute, Cleveland Clinic, Cleveland, USA.
  • Kudernatsch M; Cologne Center for Genomics (CCG), Medical Faculty of the University of Cologne, University Hospital of Cologne, 50931, Cologne, Germany.
  • Hamer H; Center for Neuropathology and Prion Research, LMU Munich, Munich, Germany.
  • Brandner S; Center for Neuropathology and Prion Research, LMU Munich, Munich, Germany.
  • Rössler K; Department of Epileptology (Krankenhaus Mara), Medical School, Bielefeld University, Bielefeld, 33617, Germany.
  • Blümcke I; Department of Epileptology (Krankenhaus Mara), Medical School, Bielefeld University, Bielefeld, 33617, Germany.
  • Jabari S; Department of Neurosurgery (Evangelisches Klinikum Bethel), Medical School, Bielefeld University, Bielefeld, 33617, Germany.
Acta Neuropathol ; 145(6): 815-827, 2023 06.
Article en En | MEDLINE | ID: mdl-36973520

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ganglioglioma / Epilepsia Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Acta Neuropathol Año: 2023 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ganglioglioma / Epilepsia Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Acta Neuropathol Año: 2023 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania