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Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis.
Chua, Bernadette A; Lennan, Connor J; Sunshine, Mary Jean; Dreifke, Daniela; Chawla, Ashu; Bennett, Eric J; Signer, Robert A J.
Afiliación
  • Chua BA; Division of Regenerative Medicine, Department of Medicine, Sanford Stem Cell Institute, Moores Cancer Center, University of California at San Diego, La Jolla, CA 92093, USA.
  • Lennan CJ; Division of Regenerative Medicine, Department of Medicine, Sanford Stem Cell Institute, Moores Cancer Center, University of California at San Diego, La Jolla, CA 92093, USA.
  • Sunshine MJ; Division of Regenerative Medicine, Department of Medicine, Sanford Stem Cell Institute, Moores Cancer Center, University of California at San Diego, La Jolla, CA 92093, USA.
  • Dreifke D; Division of Regenerative Medicine, Department of Medicine, Sanford Stem Cell Institute, Moores Cancer Center, University of California at San Diego, La Jolla, CA 92093, USA.
  • Chawla A; La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
  • Bennett EJ; Section of Cell and Developmental Biology, University of California at San Diego, La Jolla, CA 92093, USA.
  • Signer RAJ; Division of Regenerative Medicine, Department of Medicine, Sanford Stem Cell Institute, Moores Cancer Center, University of California at San Diego, La Jolla, CA 92093, USA. Electronic address: rsigner@ucsd.edu.
Cell Stem Cell ; 30(4): 460-472.e6, 2023 04 06.
Article en En | MEDLINE | ID: mdl-36948186

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteostasis / Macroautofagia Idioma: En Revista: Cell Stem Cell Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteostasis / Macroautofagia Idioma: En Revista: Cell Stem Cell Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos