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Sarcopenia is an independent risk factor for failure to achieve the 1-year MCID of the KOOS, JR and PROMIS PF-SF10a after TKA.
Humphrey, Tyler J; Salimy, Mehdi S; Jancuska, Jeffrey M; Egan, Cameron R; Melnic, Christopher M; Alpaugh, Kyle; Bedair, Hany S.
Afiliación
  • Humphrey TJ; Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, United States; Kaplan Joint Center, Newton-Wellesley Hospital, Newton, MA, United States. Electronic address: tjhumphrey@mgh.harvard.edu.
  • Salimy MS; Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, United States. Electronic address: msalimy@mgh.harvard.edu.
  • Jancuska JM; Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, United States; Kaplan Joint Center, Newton-Wellesley Hospital, Newton, MA, United States. Electronic address: jjancuska@mgh.harvard.edu.
  • Egan CR; Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, United States; Kaplan Joint Center, Newton-Wellesley Hospital, Newton, MA, United States. Electronic address: cegan3@partners.org.
  • Melnic CM; Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, United States; Kaplan Joint Center, Newton-Wellesley Hospital, Newton, MA, United States. Electronic address: cmelnic@mgh.harvard.edu.
  • Alpaugh K; Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, United States; Kaplan Joint Center, Newton-Wellesley Hospital, Newton, MA, United States. Electronic address: kalpaugh@mgh.harvard.edu.
  • Bedair HS; Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, United States; Kaplan Joint Center, Newton-Wellesley Hospital, Newton, MA, United States. Electronic address: hbedair@mgh.harvard.edu.
Knee ; 42: 64-72, 2023 Jun.
Article en En | MEDLINE | ID: mdl-36913864
BACKGROUND: Sarcopenia, which is a progressive and multifactorial condition of decreased muscle strength, has been identified as an independent predictor for falls, revision, infection, and readmissions following total knee arthroplasty (TKA), but its association to patient reported outcomes (PROMs) is less studied. The aim of this study is to determine if sarcopenia and other measures of body composition are correlated with ability to achieve the 1-year minimal clinically important difference (MCID) of the KOOS JR and PROMIS-PF-SF10a following primary TKA. METHODS: A multicenter retrospective case-control study was performed. Inclusion criteria consisted of patients over the age of 18 undergoing primary TKA, body composition metrics determined by computed tomography (CT), and available pre- and post-operative PROM scores. Predictors of achievement of the 1-year MCID of the KOOS JR and PROMIS PF-SF-10a were determined through a multivariate linear regression. RESULTS: 140 primary TKAs met inclusion criteria. 74 (52.85%) patients achieved the 1-year KOOS, JR MCID and 108 (77.41%) patients achieved the 1-year MCID for the PROMIS PF-SF10a. Sarcopenia was independently associated with decreased odds of achieving the MCID of both the KOOS, JR (OR 0.31, 95%CI 0.10-0.97, p = 0.04) and the PROMIS-PF-SF10a (OR 0.32, 95%CI 0.12-0.85, p = 0.02) CONCLUSIONS: In our study, sarcopenia was independently associated with increased odds of failure to achieve the 1-year MCID of the KOOS, JR and PROMIS PF-SF10a after TKA. Early identification of sarcopenic patients may be beneficial for arthroplasty surgeons so that targeted nutritional counseling and exercises can be recommended prior to TKA.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artroplastia de Reemplazo de Rodilla / Sarcopenia Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Adult / Humans / Middle aged Idioma: En Revista: Knee Asunto de la revista: ORTOPEDIA Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artroplastia de Reemplazo de Rodilla / Sarcopenia Tipo de estudio: Clinical_trials / Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Adult / Humans / Middle aged Idioma: En Revista: Knee Asunto de la revista: ORTOPEDIA Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos