Your browser doesn't support javascript.
loading
Advances in Boron Neutron Capture Therapy (BNCT) for Recurrent Intracranial Meningioma.
Lan, Tien-Li; Lin, Chun-Fu; Lee, Yi-Yen; Lin, Ko-Han; Chang, Feng-Chi; Lin, Shih-Chieh; Lee, Jia-Cheng; Chou, Fong-In; Peir, Jinn-Jer; Liu, Hong-Ming; Mu, Pei-Fan; Chen, Yi-Wei.
Afiliación
  • Lan TL; Department of Heavy Particles and Radiation Oncology, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Beitou Dist., Taipei City 11217, Taiwan.
  • Lin CF; Division of General Neurosurgery, Taipei Veterans General Hospital Neurosurgical Department, No.201, Sec. 2, Shipai Rd., Beitou Dist., Taipei City 11217, Taiwan.
  • Lee YY; Division of General Neurosurgery, Taipei Veterans General Hospital Neurosurgical Department, No.201, Sec. 2, Shipai Rd., Beitou Dist., Taipei City 11217, Taiwan.
  • Lin KH; Department of Nuclear Medicinel, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Beitou Dist., Taipei City 11217, Taiwan.
  • Chang FC; Division of Neuroradiology, Department of Radiology, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Beitou Dist., Taipei City 11217, Taiwan.
  • Lin SC; Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Beitou Dist., Taipei City 11217, Taiwan.
  • Lee JC; Department of Heavy Particles and Radiation Oncology, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Beitou Dist., Taipei City 11217, Taiwan.
  • Chou FI; Institute of Nuclear Engineering and Science, National Tsing Hua University, No.101, Sec 2, Kuang-Fu Rd., Hsinchu 300044, Taiwan.
  • Peir JJ; Institute of Nuclear Engineering and Science, National Tsing Hua University, No.101, Sec 2, Kuang-Fu Rd., Hsinchu 300044, Taiwan.
  • Liu HM; Institute of Nuclear Engineering and Science, National Tsing Hua University, No.101, Sec 2, Kuang-Fu Rd., Hsinchu 300044, Taiwan.
  • Mu PF; Institute of Clinical Nursing, National Yang Ming Chiao Tung University, No.155, Sec. 2, Linong St. Beitou Dist., Taipei City 112304, Taiwan.
  • Chen YW; Department of Heavy Particles and Radiation Oncology, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Beitou Dist., Taipei City 11217, Taiwan.
Int J Mol Sci ; 24(5)2023 Mar 04.
Article en En | MEDLINE | ID: mdl-36902408
Meningiomas are the most frequently diagnosed primary intracranial tumors in adults. Surgical resection is preferred if the meningioma is accessible; for those that are not suitable for surgical resection, radiotherapy should be considered to improve local tumor control. However, recurrent meningiomas are challenging to treat, as the recurrent tumor might be located in the previously irradiated area. Boron Neutron Capture Therapy (BNCT) is a highly selective radiotherapy modality in which the cytotoxic effect focuses mainly on cells with increased uptake of boron-containing drugs. In this article, we describe four patients with recurrent meningiomas treated with BNCT in Taiwan. The mean boron-containing drug tumor-to-normal tissue uptake ratio was 4.125, and the tumor mean dose was 29.414 GyE, received via BNCT. The treatment response showed two stable diseases, one partial response, and one complete response. We also introduce and support the effectiveness and safety of BNCT as an alternative salvage treatment for recurrent meningiomas.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Terapia por Captura de Neutrón de Boro / Neoplasias Meníngeas / Meningioma Límite: Adult / Humans Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Terapia por Captura de Neutrón de Boro / Neoplasias Meníngeas / Meningioma Límite: Adult / Humans Idioma: En Revista: Int J Mol Sci Año: 2023 Tipo del documento: Article País de afiliación: Taiwán Pais de publicación: Suiza