Your browser doesn't support javascript.
loading
Results of DUET: A Web-Based Weight Loss Randomized Controlled Feasibility Trial among Cancer Survivors and Their Chosen Partners.
Demark-Wahnefried, Wendy; Oster, Robert A; Crane, Tracy E; Rogers, Laura Q; Cole, W Walker; Kaur, Harleen; Farrell, David; Parrish, Kelsey B; Badr, Hoda J; Wolin, Kathleen Y; Pekmezi, Dori W.
Afiliación
  • Demark-Wahnefried W; Department of Nutrition Sciences, University of Alabama at Birmingham (UAB), Birmingham, AL 35294, USA.
  • Oster RA; O'Neal Comprehensive Cancer Center at UAB, Birmingham, AL 35233, USA.
  • Crane TE; O'Neal Comprehensive Cancer Center at UAB, Birmingham, AL 35233, USA.
  • Rogers LQ; Department of Preventive Medicine, UAB, Birmingham, AL 35233, USA.
  • Cole WW; Department of Medical Oncology, University of Miami, Miami, FL 33124, USA.
  • Kaur H; O'Neal Comprehensive Cancer Center at UAB, Birmingham, AL 35233, USA.
  • Farrell D; Department of Preventive Medicine, UAB, Birmingham, AL 35233, USA.
  • Parrish KB; Department of Health Behavior, UAB, Birmingham, AL 35294, USA.
  • Badr HJ; Department of Nutrition Sciences, University of Alabama at Birmingham (UAB), Birmingham, AL 35294, USA.
  • Wolin KY; People Designs, Inc., Durham, NC 27705, USA.
  • Pekmezi DW; Department of Health Behavior, UAB, Birmingham, AL 35294, USA.
Cancers (Basel) ; 15(5)2023 Mar 03.
Article en En | MEDLINE | ID: mdl-36900368
(1) Background: A healthful diet, regular physical activity, and weight management are cornerstones for cancer prevention and control. Yet, adherence is low in cancer survivors and others, calling for innovative solutions. Daughters, dUdes, mothers, and othErs fighting cancer Together (DUET) is a 6-month, online, diet-and-exercise, weight-loss intervention to improve health behaviors and outcomes among cancer survivor-partner dyads. (2) Methods: DUET was tested in 56 dyads (survivors of obesity-related cancers and chosen partners) (n = 112), both with overweight/obesity, sedentary behavior, and suboptimal diets. After baseline assessment, dyads were randomized to DUET intervention or waitlist control arms; data were collected at 3- and 6-months and analyzed using chi-square, t-tests, and mixed linear models (α < 0.05). (3) Results: Retention was 89% and 100% in waitlisted and intervention arms, respectively. Dyad weight loss (primary outcome) averaged -1.1 (waitlist) vs. -2.8 kg (intervention) (p = 0.044/time-by-arm interaction p = 0.033). Caloric intake decreased significantly in DUET survivors versus controls (p = 0.027). Evidence of benefit was observed for physical activity and function, blood glucose, and c-reactive protein. Dyadic terms were significant across outcomes, suggesting that the partner-based approach contributed to intervention-associated improvements. (4) Conclusions: DUET represents a pioneering effort in scalable, multi-behavior weight management interventions to promote cancer prevention and control, calling for studies that are larger in size, scope, and duration.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Cancers (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Cancers (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza