Irreversible evolutionary loss of chitin-degrading ability in the chitinase-like protein Ym1 under positive selection in rodents.

Okawa, Kazuaki; Tabata, Eri; Kida, Yuta; Uno, Kyohei; Suzuki, Hidetoshi; Kamaya, Minori; Bauer, Peter O; Oyama, Fumitaka

Okawa, Kazuaki; Tabata, Eri; Kida, Yuta; Uno, Kyohei; Suzuki, Hidetoshi; Kamaya, Minori; Bauer, Peter O; Oyama, Fumitaka.

Afiliación

Okawa K; Department of Chemistry and Life Science, Kogakuin University, Tokyo, Japan.
Tabata E; Department of Chemistry and Life Science, Kogakuin University, Tokyo, Japan.
Kida Y; Japan Society for the Promotion of Science (PD), Tokyo, Japan.
Uno K; Department of Chemistry and Life Science, Kogakuin University, Tokyo, Japan.
Suzuki H; Department of Chemistry and Life Science, Kogakuin University, Tokyo, Japan.
Kamaya M; Department of Chemistry and Life Science, Kogakuin University, Tokyo, Japan.
Bauer PO; Department of Applied Chemistry, Kogakuin University, Tokyo, Japan.
Oyama F; Bioinova a.s, Prague, Czech Republic.

Protein Sci ; 32(4): e4620, 2023 04.

Article en En | MEDLINE | ID: mdl-36883357

Asunto(s)

Quitinasas; Animales; Ratones; Sustitución de Aminoácidos; Evolución Biológica; Quitina/química; Quitinasas/química

Palabras clave

chitin; chitinase; chitinase-like protein Ym1; enzyme inactivation; mouse

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quitinasas Límite: Animals Idioma: En Revista: Protein Sci Asunto de la revista: BIOQUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

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