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Investigating the genetic basis of vertebrate dispersal combining RNA-seq, RAD-seq and quantitative genetics.
San-Jose, Luis M; Bestion, Elvire; Pellerin, Félix; Richard, Murielle; Di Gesu, Lucie; Salmona, Jordi; Winandy, Laurane; Legrand, Delphine; Bonneaud, Camille; Guillaume, Olivier; Calvez, Olivier; Elmer, Kathryn R; Yurchenko, Andrey A; Recknagel, Hans; Clobert, Jean; Cote, Julien.
Afiliación
  • San-Jose LM; Laboratoire Évolution and Diversité Biologique, UMR 5174, CNRS, Université Toulouse III Paul Sabatier, IRD, Toulouse, France.
  • Bestion E; Station d'Ecologie Théorique et Expérimentale, UAR 2029, CNRS, Moulis, France.
  • Pellerin F; Laboratoire Évolution and Diversité Biologique, UMR 5174, CNRS, Université Toulouse III Paul Sabatier, IRD, Toulouse, France.
  • Richard M; Station d'Ecologie Théorique et Expérimentale, UAR 2029, CNRS, Moulis, France.
  • Di Gesu L; Laboratoire Évolution and Diversité Biologique, UMR 5174, CNRS, Université Toulouse III Paul Sabatier, IRD, Toulouse, France.
  • Salmona J; Laboratoire Évolution and Diversité Biologique, UMR 5174, CNRS, Université Toulouse III Paul Sabatier, IRD, Toulouse, France.
  • Winandy L; Laboratoire Évolution and Diversité Biologique, UMR 5174, CNRS, Université Toulouse III Paul Sabatier, IRD, Toulouse, France.
  • Legrand D; Station d'Ecologie Théorique et Expérimentale, UAR 2029, CNRS, Moulis, France.
  • Bonneaud C; Centre for Ecology and Conservation, Biosciences, University of Exeter, Penryn, Cornwall, UK.
  • Guillaume O; Station d'Ecologie Théorique et Expérimentale, UAR 2029, CNRS, Moulis, France.
  • Calvez O; Station d'Ecologie Théorique et Expérimentale, UAR 2029, CNRS, Moulis, France.
  • Elmer KR; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  • Yurchenko AA; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  • Recknagel H; Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  • Clobert J; Station d'Ecologie Théorique et Expérimentale, UAR 2029, CNRS, Moulis, France.
  • Cote J; Laboratoire Évolution and Diversité Biologique, UMR 5174, CNRS, Université Toulouse III Paul Sabatier, IRD, Toulouse, France.
Mol Ecol ; 32(12): 3060-3075, 2023 06.
Article en En | MEDLINE | ID: mdl-36872057
Although animal dispersal is known to play key roles in ecological and evolutionary processes such as colonization, population extinction and local adaptation, little is known about its genetic basis, particularly in vertebrates. Untapping the genetic basis of dispersal should deepen our understanding of how dispersal behaviour evolves, the molecular mechanisms that regulate it and link it to other phenotypic aspects in order to form the so-called dispersal syndromes. Here, we comprehensively combined quantitative genetics, genome-wide sequencing and transcriptome sequencing to investigate the genetic basis of natal dispersal in a known ecological and evolutionary model of vertebrate dispersal: the common lizard, Zootoca vivipara. Our study supports the heritability of dispersal in semi-natural populations, with less variation attributable to maternal and natal environment effects. In addition, we found an association between natal dispersal and both variation in the carbonic anhydrase (CA10) gene, and in the expression of several genes (TGFB2, SLC6A4, NOS1) involved in central nervous system functioning. These findings suggest that neurotransmitters (serotonin and nitric oxide) are involved in the regulation of dispersal and shaping dispersal syndromes. Several genes from the circadian clock (CRY2, KCTD21) were also differentially expressed between disperser and resident lizards, supporting that the circadian rhythm, known to be involved in long-distance migration in other taxa, might affect dispersal as well. Since neuronal and circadian pathways are relatively well conserved across vertebrates, our results are likely to be generalisable, and we therefore encourage future studies to further investigate the role of these pathways in shaping dispersal in vertebrates.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vertebrados / Evolución Biológica Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Ecol Asunto de la revista: BIOLOGIA MOLECULAR / SAUDE AMBIENTAL Año: 2023 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vertebrados / Evolución Biológica Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Ecol Asunto de la revista: BIOLOGIA MOLECULAR / SAUDE AMBIENTAL Año: 2023 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido