Ethical principles for the usage and sharing of genomic data from researc.
Cas Lek Cesk
; 161(7-8): 271-275, 2023.
Article
en En
| MEDLINE
| ID: mdl-36868836
The current significant development of human genome/exome sequencing in biomedical research is one of the important paths leading to personalized medicine. However, sequencing of human genetic information generates potentially sensitive and exploitable data, which leads to ethical, legal, and security issues. For this reason, it is necessary to follow several measures when working with these data, applying to their entire life cycle - i.e., acquisition, storage, processing, usage, sharing, archiving, and reuse. In addition, importance of good practice during the whole data life cycle is emphasized by current European trends towards open science and digital transformation. Therefore, the following recommendations have been developed, establishing principles for work with the whole human genome sequences or parts of it in research context. The recommendations are based on two documents published by the Global Alliance for Genomics and Health (GA4GH) and on foreign literature, thus summarizing recent relevant guidance on most aspects of working with human genomic data.
Palabras clave
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Genómica
/
Medicina de Precisión
Tipo de estudio:
Guideline
Aspecto:
Ethics
Límite:
Humans
Idioma:
En
Revista:
Cas Lek Cesk
Año:
2023
Tipo del documento:
Article
Pais de publicación:
República Checa