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Unsaturated bond recognition leads to biased signal in a fatty acid receptor.
Mao, Chunyou; Xiao, Peng; Tao, Xiao-Na; Qin, Jiao; He, Qing-Tao; Zhang, Chao; Guo, Sheng-Chao; Du, Ya-Qin; Chen, Li-Nan; Shen, Dan-Dan; Yang, Zhi-Shuai; Zhang, Han-Qiong; Huang, Shen-Ming; He, Yong-Hao; Cheng, Jie; Zhong, Ya-Ni; Shang, Pan; Chen, Jun; Zhang, Dao-Lai; Wang, Qian-Lang; Liu, Mei-Xia; Li, Guo-Yu; Guo, Yongyuan; Xu, H Eric; Wang, Chuanxin; Zhang, Cheng; Feng, Shiqing; Yu, Xiao; Zhang, Yan; Sun, Jin-Peng.
Afiliación
  • Mao C; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
  • Xiao P; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Tao XN; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Qin J; Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing 100191, China.
  • He QT; The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Zhang C; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
  • Guo SC; Department of Orthopedics, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Du YQ; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Chen LN; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Shen DD; Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing 100191, China.
  • Yang ZS; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
  • Zhang HQ; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
  • Huang SM; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • He YH; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Cheng J; Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing 100191, China.
  • Zhong YN; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Shang P; Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Chen J; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Physiology, School of Basic Medical Sciences, Shandong University, Jinan 250012, China.
  • Zhang DL; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Wang QL; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Physiology, School of Basic Medical Sciences, Shandong University, Jinan 250012, China.
  • Liu MX; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Li GY; School of Pharmacy, Binzhou Medical University, Yantai 264003, China.
  • Guo Y; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Xu HE; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Wang C; Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Zhang C; Department of Orthopedics, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Feng S; CAS Key Laboratory of Receptor Research, Center for Structure and Function of Drug Targets, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Yu X; The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
  • Zhang Y; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences, the State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine, Department of Cardiology, Q
  • Sun JP; The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan 250012, China.
Science ; 380(6640): eadd6220, 2023 04 07.
Article en En | MEDLINE | ID: mdl-36862765

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Ácidos Grasos Omega-3 / Receptores Acoplados a Proteínas G Límite: Humans Idioma: En Revista: Science Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Ácidos Grasos Omega-3 / Receptores Acoplados a Proteínas G Límite: Humans Idioma: En Revista: Science Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos