A Synthetic Biology Approach for Vaccine Candidate Design against Delta Strain of SARS-CoV-2 Revealed Disruption of Favored Codon Pair as a Better Strategy over Using Rare Codons.

Gurjar, Pankaj; Karuvantevida, Noushad; Rzhepakovsky, Igor Vladimirovich; Khan, Azmat Ali; Khandia, Rekha

Gurjar, Pankaj; Karuvantevida, Noushad; Rzhepakovsky, Igor Vladimirovich; Khan, Azmat Ali; Khandia, Rekha.

Afiliación

Gurjar P; Department of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW 2770, Australia.
Karuvantevida N; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai P.O. Box 505055, United Arab Emirates.
Rzhepakovsky IV; Medical and Biological Faculty, North Caucasus Federal University, 355017 Stavropol, Russia.
Khan AA; Pharmaceutical Biotechnology Laboratory, Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
Khandia R; Department of Biochemistry and Genetics, Barkatullah Universty, Bhopal 462026, India.

Vaccines (Basel) ; 11(2)2023 Feb 20.

Article en En | MEDLINE | ID: mdl-36851364

Palabras clave

SARS-CoV-2 delta vaccine candidate; codon context; codon optimization; codon pair; rare codon; synthetic biology

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Vaccines (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Suiza

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