A Biological OR(XNOR) Logic Gate Couples Carbon Source and Transgene Expression Switching in a <i>Komagataella phaffii</i> (<i>Pichia pastoris</i>) Strain Co-producing Process-Enhancing Lipase and a Virus-like Particle (VLP) Vaccine.

Bandyopadhyay, Sushobhan; Pavlika, Vasos; Bracewell, Daniel G; Nesbeth, Darren N

A Biological OR(XNOR) Logic Gate Couples Carbon Source and Transgene Expression Switching in a Komagataella phaffii (Pichia pastoris) Strain Co-producing Process-Enhancing Lipase and a Virus-like Particle (VLP) Vaccine.

Bandyopadhyay, Sushobhan; Pavlika, Vasos; Bracewell, Daniel G; Nesbeth, Darren N.

Afiliación

Bandyopadhyay S; Department of Biochemical Engineering, University College London, Bernard Katz Building, London WC1E 6BT, United Kingdom.
Pavlika V; Department of Biochemical Engineering, University College London, Bernard Katz Building, London WC1E 6BT, United Kingdom.
Bracewell DG; Department of Biochemical Engineering, University College London, Bernard Katz Building, London WC1E 6BT, United Kingdom.
Nesbeth DN; Department of Biochemical Engineering, University College London, Bernard Katz Building, London WC1E 6BT, United Kingdom.

ACS Synth Biol ; 12(3): 657-663, 2023 03 17.

Article en En | MEDLINE | ID: mdl-36848292

Asunto(s)

Pichia; Vacunas de Partículas Similares a Virus; Pichia/metabolismo; Vacunas de Partículas Similares a Virus/metabolismo; Lipasa/genética; Lipasa/metabolismo; Carbono/metabolismo; Metanol/metabolismo

Palabras clave

Triacylglycerol lipase; bioreactor, carbon source; logic gate; vaccine; virus-like particle

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pichia / Vacunas de Partículas Similares a Virus Idioma: En Revista: ACS Synth Biol Año: 2023 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Estados Unidos

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