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Prevalence of digestive disorders associated with imported Chagas disease (PADChI study): an observational study.
Ramírez-Olivencia, G; Arsuaga, M; Torrús, D; Belhassen-Garcia, M; Rodríguez-Guardado, A; Herrero-Mendoza, M D; Mateo-Maestre, M; Campos-Rivas, R P; Membrillo-de Novales, F J.
Afiliación
  • Ramírez-Olivencia G; Sección de Infecciosas, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain; Servicio de Medicina Interna, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain. Electronic address: germanro.76@gmail.com.
  • Arsuaga M; Sección de Infecciosas, Servicio de Medicina Interna, Hospital Universitario La Paz-Carlos III, Madrid, Spain.
  • Torrús D; Servicio de Medicina Interna, Hospital General Universitario Dr. Balmis de Alicante-Instituto de Investigación Sanitaria y Biomédica de ALICANTE (ISABIAL), Alicante, Spain.
  • Belhassen-Garcia M; Servicio de Medicina Interna, Hospital Universitario de Salamanca, Salamanca, Spain.
  • Rodríguez-Guardado A; Área de Gestión Clínica Medicina Interna, Hospital Universitario Central de Asturias, Grupo de Microbiología Traslacional, Instituto de Investigación del Principado de Asturias, Asturias, Spain.
  • Herrero-Mendoza MD; Servicio de Medicina Interna, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain.
  • Mateo-Maestre M; Servicio de Microbiología, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain.
  • Campos-Rivas RP; Servicio de Radiología, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain.
  • Membrillo-de Novales FJ; Sección de Infecciosas, Hospital Central de la Defensa Gómez Ulla, Madrid, Spain.
Rev Clin Esp (Barc) ; 223(4): 193-201, 2023 04.
Article en En | MEDLINE | ID: mdl-36842660
BACKGROUND: Chagas disease (CD) is a parasitic disease caused by Trypanosoma cruzi, in which up to 10-20% of those affected may suffer digestive disorders. Multiple studies have been carried out on CD in non-endemic countries, mainly related to cardiological involvement. However, digestive disorders have not been analyzed in such depth. The objective of the study was to determine the prevalence of digestive disorders in imported CD at the time of first care. METHODS: An observational cross-sectional descriptive analysis of imported CD was performed. Chagasic structural damage and infectious digestive comorbidity were evaluated. The association between Chagasic structural damage and heart disease in Chagas patients was also investigated. RESULTS: After reviewing a total of 1,216 medical records, those of 464 patients were selected for analysis. Globally, the prevalence of digestive disorders in imported Chagas was 57.76%, 95% CI (53.25-62.27). The prevalence of comorbidity of infectious diseases was 40.73% CI 95% (36.25-45.22). Colonic abnormalities were found in 84 of 378 barium enema patients. CD-related esophageal abnormalities were present in 63 of 380 patients studied with esophagogram. CONCLUSIONS: The prevalence of digestive disorders associated with CD is high, so the presence of infectious diseases (mainly parasitic and H. pylori infection) should be ruled out. It is important to exclude structural involvement in all symptomatic patients, and asymptomatic patients should also be considered and offered.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trypanosoma cruzi / Enfermedad de Chagas / Enfermedades del Sistema Digestivo Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Rev Clin Esp (Barc) Año: 2023 Tipo del documento: Article Pais de publicación: España
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trypanosoma cruzi / Enfermedad de Chagas / Enfermedades del Sistema Digestivo Tipo de estudio: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Rev Clin Esp (Barc) Año: 2023 Tipo del documento: Article Pais de publicación: España