Your browser doesn't support javascript.
loading
Pilomatrix Carcinoma: Report of Two Cases of the Head and Review of the Literature.
Toffoli, Ludovica; Bazzacco, Giulia; Conforti, Claudio; Guarneri, Claudio; Giuffrida, Roberta; Zelin, Enrico; di Meo, Nicola; Zalaudek, Iris.
Afiliación
  • Toffoli L; Dermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.
  • Bazzacco G; Dermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.
  • Conforti C; Dermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.
  • Guarneri C; Department of Biomedical and Dental Sciences and Morpho Functional Imaging, University of Messina, 98124 Messina, Italy.
  • Giuffrida R; Department of Clinical and Experimental Medicine, Dermatology, University of Messina, 98124 Messina, Italy.
  • Zelin E; Dermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.
  • di Meo N; Dermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.
  • Zalaudek I; Dermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.
Curr Oncol ; 30(2): 1426-1438, 2023 01 19.
Article en En | MEDLINE | ID: mdl-36826070
BACKGROUND: Pilomatrix carcinoma (PC) is a rare skin tumor arising from hair follicle matrix cells. It is locally aggressive with a high rate of local recurrence after surgical excision. Few cases in the literature have been described and the management is not well defined. OBJECTIVES: The aim of this study was to present two cases of PC located on the head and review the relevant literature about epidemiology, clinical and dermoscopic evaluation, characteristics of local and distant metastases, local recurrence rate and management of this rare skin tumor. METHODS: We consulted databases from PubMed, Research Gate and Google Scholar, from January 2012 to November 2022. We reviewed the literature and reported two additional cases. RESULTS: We selected 52 tumors in middle-aged to older patients located mostly on the head. Dermoscopy evaluation was rarely performed in the pre-operative diagnostic setting. The most definitive treatment was wide local excision, but local recurrences were common. In total, we observed 11 cases of recurrences and 9 patients with locoregional or distant metastases. Four patients received adjuvant radiotherapy, two patients needed chemotherapy and local cancer therapy and one patient received radiochemotherapy. CONCLUSION: Our reports and the review of the literature can provide a better awareness and management of this rare tumor.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Neoplasias Óseas / Neoplasias de la Mama / Carcinoma / Enfermedades del Cabello Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Curr Oncol Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Neoplasias Óseas / Neoplasias de la Mama / Carcinoma / Enfermedades del Cabello Tipo de estudio: Diagnostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Curr Oncol Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza