Estrogen downregulates CD73/adenosine axis hyperactivity via adaptive modulation PI3K/Akt signaling to prevent myocarditis and arrhythmias during chronic catecholamines stress.

Ndzie Noah, Marie Louise; Adzika, Gabriel Komla; Mprah, Richard; Adekunle, Adebayo Oluwafemi; Koda, Stephane; Adu-Amankwaah, Joseph; Xu, Yaxin; Kanwore, Kouminin; Wowui, Prosperl Ivette; Sun, Hong

Ndzie Noah, Marie Louise; Adzika, Gabriel Komla; Mprah, Richard; Adekunle, Adebayo Oluwafemi; Koda, Stephane; Adu-Amankwaah, Joseph; Xu, Yaxin; Kanwore, Kouminin; Wowui, Prosperl Ivette; Sun, Hong.

Afiliación

Ndzie Noah ML; Department of Physiology, Xuzhou Medical University, 209 Tongshan Road, XuzhouJiangsu, 221004, China.
Adzika GK; Department of Physiology, Xuzhou Medical University, 209 Tongshan Road, XuzhouJiangsu, 221004, China.
Mprah R; Department of Physiology, Xuzhou Medical University, 209 Tongshan Road, XuzhouJiangsu, 221004, China.
Adekunle AO; Department of Physiology, Xuzhou Medical University, 209 Tongshan Road, XuzhouJiangsu, 221004, China.
Koda S; Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Xuzhou Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, China.
Adu-Amankwaah J; Department of Physiology, Xuzhou Medical University, 209 Tongshan Road, XuzhouJiangsu, 221004, China.
Xu Y; Department of Physiology, Xuzhou Medical University, 209 Tongshan Road, XuzhouJiangsu, 221004, China.
Kanwore K; Public Experimental Research Center, Department of Neurobiology and Anatomy, Xuzhou Medical University, Xuzhou, China.
Wowui PI; Department of Physiology, Xuzhou Medical University, 209 Tongshan Road, XuzhouJiangsu, 221004, China.
Sun H; Department of Physiology, Xuzhou Medical University, 209 Tongshan Road, XuzhouJiangsu, 221004, China. sunh@xzhmu.edu.cn.

Cell Commun Signal ; 21(1): 41, 2023 02 23.

Article en En | MEDLINE | ID: mdl-36823590

Asunto(s)

Adenosina; Miocarditis; Femenino; Ratones; Animales; Adenosina/farmacología; Proteínas Proto-Oncogénicas c-akt/metabolismo; Fosfatidilinositol 3-Quinasas/metabolismo; Catecolaminas; Isoproterenol/farmacología; Arritmias Cardíacas; Estrógenos/farmacología; Apoptosis

Palabras clave

Adenosine; CD73; Cardiac inflammation; Catecholamine stress; Estrogen

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adenosina / Miocarditis Límite: Animals Idioma: En Revista: Cell Commun Signal Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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