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Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein.
Janssen, Kobe; Claes, Filip; Van de Velde, Dido; Wehbi, Vanessa L; Houben, Bert; Lampi, Yulia; Nys, Mieke; Khodaparast, Laleh; Khodaparast, Ladan; Louros, Nikolaos; van der Kant, Rob; Verniers, Joffre; Garcia, Teresa; Ramakers, Meine; Konstantoulea, Katerina; Maragkou, Katerina; Duran-Romaña, Ramon; Musteanu, Mónica; Barbacid, Mariano; Scorneaux, Bernard; Beirnaert, Els; Schymkowitz, Joost; Rousseau, Frederic.
Afiliación
  • Janssen K; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium.
  • Claes F; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven 3000, Leuven, Belgium.
  • Van de Velde D; Aelin Therapeutics, 3001 Leuven, Belgium.
  • Wehbi VL; Aelin Therapeutics, 3001 Leuven, Belgium.
  • Houben B; Aelin Therapeutics, 3001 Leuven, Belgium.
  • Lampi Y; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium.
  • Nys M; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven 3000, Leuven, Belgium.
  • Khodaparast L; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium.
  • Khodaparast L; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven 3000, Leuven, Belgium.
  • Louros N; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium.
  • van der Kant R; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven 3000, Leuven, Belgium.
  • Verniers J; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium.
  • Garcia T; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven 3000, Leuven, Belgium.
  • Ramakers M; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium.
  • Konstantoulea K; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven 3000, Leuven, Belgium.
  • Maragkou K; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium.
  • Duran-Romaña R; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven 3000, Leuven, Belgium.
  • Musteanu M; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium.
  • Barbacid M; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven 3000, Leuven, Belgium.
  • Scorneaux B; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium.
  • Beirnaert E; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven 3000, Leuven, Belgium.
  • Schymkowitz J; Switch Laboratory, VIB-KU Leuven Center for Brain and Disease Research, 3000 Leuven, Belgium.
  • Rousseau F; Switch Laboratory, Department of Cellular and Molecular Medicine, KU Leuven 3000, Leuven, Belgium.
Proc Natl Acad Sci U S A ; 120(9): e2214921120, 2023 02 28.
Article en En | MEDLINE | ID: mdl-36812200
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas p21(ras) / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Proto-Oncogénicas p21(ras) / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Estados Unidos