Design, synthesis and anti-Chikungunya virus activity of lomerizine derivatives.

Chen, Chu-Ran; Ma, Ying; Wang, Han-Xuan; Liu, Xin-Yang; Liu, Yan; Meng, Qing-Guo; Jin, Yong-Sheng

Chen, Chu-Ran; Ma, Ying; Wang, Han-Xuan; Liu, Xin-Yang; Liu, Yan; Meng, Qing-Guo; Jin, Yong-Sheng.

Afiliación

Chen CR; School of Pharmacy, Naval Medical University, Shanghai 200433, China.
Ma Y; School of Pharmacy, Yantai University, Yantai, Shandong Province 264005, China.
Wang HX; Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai 200433, China.
Liu XY; School of Basic Medicine, Naval Medical University, Shanghai 200433, China.
Liu Y; Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Meng QG; School of Pharmacy, Yantai University, Yantai, Shandong Province 264005, China.
Jin YS; School of Pharmacy, Naval Medical University, Shanghai 200433, China. Electronic address: ysjinsmmu@163.com.

Bioorg Med Chem Lett ; 83: 129188, 2023 03 01.

Article en En | MEDLINE | ID: mdl-36804408

Asunto(s)

Fiebre Chikungunya; Virus Chikungunya; Animales; Humanos; Simulación del Acoplamiento Molecular; Fiebre Chikungunya/tratamiento farmacológico; Antivirales/metabolismo; Replicación Viral

Palabras clave

ADMET; CHIKV; Docking; Lomerizine; Synthesis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus Chikungunya / Fiebre Chikungunya Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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