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Lurasidone for the treatment of schizophrenia in adult and paediatric populations.
Guilera, Teresa; Chart Pascual, Juan Pablo; Blasco, Maria Del Carmen; Calvo Estopiñán, Pilar; Piernas González, Rubén Asensio; Ramírez Martínez, Isabel; Rodríguez Moyano, Cristóbal; Prieto Pérez, Rita; Gabarda-Inat, Irene; Prados-Ojeda, Juan L; Diaz-Marsà, Marina; Martín-Carrasco, Manuel.
Afiliación
  • Guilera T; Psychiatry Service, Santa Maria University Hospital, Lleida, Spain.
  • Chart Pascual JP; Institute for Biomedical Research in Lleida Dr Pifarré Foundation (IRBLleida), Lleida, Spain.
  • Blasco MDC; Hospital Universitario Araba, Vitoria, Spain.
  • Calvo Estopiñán P; Psychiatry Service, Hospital Universitario Miguel Servet, Zaragoza, Spain.
  • Piernas González RA; Psychiatry Service, Hospital Universitario Miguel Servet, Zaragoza, Spain.
  • Ramírez Martínez I; Hospital Universitario Torrecárdenas, Almería, Spain.
  • Rodríguez Moyano C; Hospital Universitario Torrecárdenas, Almería, Spain.
  • Prieto Pérez R; Hospital Universitario Torrecárdenas, Almería, Spain.
  • Gabarda-Inat I; Hospital Marítimo de Oza (CHUAC, Coruña), La Coruña, Spain.
  • Prados-Ojeda JL; Angelini Pharma España SLU, Medical Department, Barcelona, Spain.
  • Diaz-Marsà M; Servicio de Salud Mental, Hospital Universitario Reina Sofía, Córdoba, Spain.
  • Martín-Carrasco M; Departamento de Ciencias Morfológicas y Sociosanitarias, Universidad de Córdoba, Córdoba, Spain.
Drugs Context ; 122023.
Article en En | MEDLINE | ID: mdl-36793449
Schizophrenia is a common debilitating disorder characterized by significant impairments in how reality is perceived, combined with behavioural changes. In this review, we describe the lurasidone development programme for adult and paediatric patients. Both the pharmacokinetic and pharmacodynamic characteristics of lurasidone are revisited. In addition, pivotal clinical studies conducted on both adults and children are summarized. Several clinical cases, which demonstrate the role of lurasidone in real-world practice, are also presented. Current clinical guidelines recommend lurasidone as the first-line treatment in the acute and long-term management of schizophrenia in both adult and paediatric populations.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline Idioma: En Revista: Drugs Context Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline Idioma: En Revista: Drugs Context Año: 2023 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido