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Respiratory infections and type 1 diabetes: Potential roles in pathogenesis.
Wu, Roy; Mumtaz, Mohsin; Maxwell, Anna J; Isaacs, Sonia R; Laiho, Jutta E; Rawlinson, William D; Hyöty, Heikki; Craig, Maria E; Kim, Ki Wook.
Afiliación
  • Wu R; Discipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.
  • Mumtaz M; Virology and Serology Division, New South Wales Health Pathology, Prince of Wales Hospital, Randwick, New South Wales, Australia.
  • Maxwell AJ; Discipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.
  • Isaacs SR; Virology and Serology Division, New South Wales Health Pathology, Prince of Wales Hospital, Randwick, New South Wales, Australia.
  • Laiho JE; Discipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.
  • Rawlinson WD; Virology and Serology Division, New South Wales Health Pathology, Prince of Wales Hospital, Randwick, New South Wales, Australia.
  • Hyöty H; Discipline of Paediatrics and Child Health, School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Randwick, New South Wales, Australia.
  • Craig ME; Virology and Serology Division, New South Wales Health Pathology, Prince of Wales Hospital, Randwick, New South Wales, Australia.
  • Kim KW; Department of Virology, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Rev Med Virol ; 33(2): e2429, 2023 03.
Article en En | MEDLINE | ID: mdl-36790804
Among the environmental factors associated with type 1 diabetes (T1D), viral infections of the gut and pancreas has been investigated most intensely, identifying enterovirus infections as the prime candidate trigger of islet autoimmunity (IA) and T1D development. However, the association between respiratory tract infections (RTI) and IA/T1D is comparatively less known. While there are significant amounts of epidemiological evidence supporting the role of respiratory infections in T1D, there remains a paucity of data characterising infectious agents at the molecular level. This gap in the literature precludes the identification of the specific infectious agents driving the association between RTI and T1D. Furthermore, the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on the development of IA/T1D remains undeciphered. Here, we provide a comprehensive overview of the evidence to date, implicating RTIs (viral and non-viral) as potential risk factors for IA/T1D.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones del Sistema Respiratorio / Islotes Pancreáticos / Diabetes Mellitus Tipo 1 / COVID-19 Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Rev Med Virol Asunto de la revista: VIROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones del Sistema Respiratorio / Islotes Pancreáticos / Diabetes Mellitus Tipo 1 / COVID-19 Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Rev Med Virol Asunto de la revista: VIROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Reino Unido