Laboratory and clinical features of self-poisoning with salbutamol and terbutaline.

Jarvie, D R; Thompson, A M; Dyson, E H

Jarvie, D R; Thompson, A M; Dyson, E H.

Afiliación

Jarvie DR; Department of Clinical Chemistry, Royal Infirmary, Edinburgh, Scotland, UK.

Clin Chim Acta ; 168(3): 313-22, 1987 Oct 15.

Article en En | MEDLINE | ID: mdl-3677429

RESUMEN

A method has been developed for the simultaneous determination of the sympathomimetic drugs salbutamol and terbutaline in the plasma of poisoned patients, using ion-pair high-performance liquid chromatography with amperometric detection. Plasma concentrations of the drugs, measured in 8 poisoned patients, were well above the therapeutic range. The clinical and metabolic effects of overdose with these drugs were considerably less severe than those seen in patients with plasma theophylline concentrations elevated to the same degree.

Asunto(s)

Albuterol/envenenamiento; Intento de Suicidio; Terbutalina/envenenamiento; Albuterol/sangre; Cromatografía Líquida de Alta Presión/métodos; Electroquímica/métodos; Humanos; Terbutalina/sangre

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Intento de Suicidio / Terbutalina / Albuterol Límite: Humans Idioma: En Revista: Clin Chim Acta Año: 1987 Tipo del documento: Article Pais de publicación: Países Bajos

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