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A sulphated glycosaminoglycan extract from Placopecten magellanicus inhibits the Alzheimer's disease ß-site amyloid precursor protein cleaving enzyme 1 (BACE-1).
Mycroft-West, Courtney J; Devlin, Anthony J; Cooper, Lynsay C; Guimond, Scott E; Procter, Patricia; Miller, Gavin J; Guerrini, Marco; Fernig, David G; Yates, Edwin A; Lima, Marcelo A; Skidmore, Mark A.
Afiliación
  • Mycroft-West CJ; Centre for Glycoscience Research and Training, Keele University, Keele, Staffordshire, ST5 5BG, UK. Electronic address: courtney.mycroft-west@rfi.ac.uk.
  • Devlin AJ; Centre for Glycoscience Research and Training, Keele University, Keele, Staffordshire, ST5 5BG, UK; Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni, Via G. Colombo 81, 20133, Milan, Italy. Electronic address: anthony.devlin@rfi.ac.uk.
  • Cooper LC; University of Gloucestershire, Francis Close Hall Campus, Swindon Rd, Cheltenham, GL50 4AZ, UK. Electronic address: lcooper1@glos.ac.uk.
  • Guimond SE; Centre for Glycoscience Research and Training, Keele University, Keele, Staffordshire, ST5 5BG, UK. Electronic address: s.e.guimond@keele.ac.uk.
  • Procter P; Centre for Glycoscience Research and Training, Keele University, Keele, Staffordshire, ST5 5BG, UK. Electronic address: p.procter@keele.ac.uk.
  • Miller GJ; Centre for Glycoscience Research and Training, Keele University, Keele, Staffordshire, ST5 5BG, UK. Electronic address: g.j.miller@keele.ac.uk.
  • Guerrini M; Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni, Via G. Colombo 81, 20133, Milan, Italy. Electronic address: guerrini@ronzoni.it.
  • Fernig DG; Department of Biochemistry and Systems Biology, ISMIB, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK. Electronic address: dgfernig@liverpool.ac.uk.
  • Yates EA; Department of Biochemistry and Systems Biology, ISMIB, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK. Electronic address: E.A.Yates@liverpool.ac.uk.
  • Lima MA; Centre for Glycoscience Research and Training, Keele University, Keele, Staffordshire, ST5 5BG, UK. Electronic address: m.andrade.de.lima@keele.ac.uk.
  • Skidmore MA; Centre for Glycoscience Research and Training, Keele University, Keele, Staffordshire, ST5 5BG, UK; Department of Biochemistry and Systems Biology, ISMIB, University of Liverpool, Crown Street, Liverpool, L69 7ZB, UK. Electronic address: m.a.skidmore@keele.ac.uk.
Carbohydr Res ; 525: 108747, 2023 Mar.
Article en En | MEDLINE | ID: mdl-36773398

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pectinidae / Enfermedad de Alzheimer Límite: Animals Idioma: En Revista: Carbohydr Res Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pectinidae / Enfermedad de Alzheimer Límite: Animals Idioma: En Revista: Carbohydr Res Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos