Cardiovascular effects of bufotenin on human 5-HT<sub>4</sub> serotonin receptors in cardiac preparations of transgenic mice and in human atrial preparations.

Neumann, Joachim; Schulz, Nils; Fehse, Charlotte; Azatsian, Karyna; Cináková, Aneta; Marusáková, Margaréta; Hofmann, Britt; Gergs, Ulrich

Cardiovascular effects of bufotenin on human 5-HT₄ serotonin receptors in cardiac preparations of transgenic mice and in human atrial preparations.

Neumann, Joachim; Schulz, Nils; Fehse, Charlotte; Azatsian, Karyna; Cináková, Aneta; Marusáková, Margaréta; Hofmann, Britt; Gergs, Ulrich.

Afiliación

Neumann J; Institute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, D-06097, Halle, Germany.
Schulz N; Institute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, D-06097, Halle, Germany.
Fehse C; Institute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, D-06097, Halle, Germany.
Azatsian K; Institute for Pharmacology and Toxicology, Medical Faculty, Martin Luther University Halle-Wittenberg, D-06097, Halle, Germany.
Cináková A; Faculty of Pharmacy, Gdansk Medical University, Gdansk, Poland.
Marusáková M; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University, Bratislava, Slovakia.
Hofmann B; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Comenius University, Bratislava, Slovakia.
Gergs U; Cardiac Surgery, Medical Faculty, Martin Luther University Halle-Wittenberg, D-06097, Halle, Germany.

Naunyn Schmiedebergs Arch Pharmacol ; 396(7): 1471-1485, 2023 07.

Article en En | MEDLINE | ID: mdl-36754881

Asunto(s)

Fibrilación Atrial; Serotonina; Ratones; Animales; Humanos; Serotonina/farmacología; Ratones Transgénicos; Bufotenina/farmacología; Contracción Miocárdica; Receptores de Serotonina 5-HT4/genética; Atrios Cardíacos; Receptores de Serotonina

Palabras clave

5-HT4-receptor; Bufotenin; Chronotropy; Human atrium; Inotropy; Pargyline; Serotonin; Transgenic mice; Tropisetron; Tryptamine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fibrilación Atrial / Serotonina Límite: Animals / Humans Idioma: En Revista: Naunyn Schmiedebergs Arch Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Alemania

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