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Tuning liver pyruvate kinase activity up or down with a new class of allosteric modulators.
Nain-Perez, Amalyn; Nilsson, Oscar; Lulla, Aleksei; Håversen, Liliana; Brear, Paul; Liljenberg, Sara; Hyvönen, Marko; Borén, Jan; Grøtli, Morten.
Afiliación
  • Nain-Perez A; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96, Gothenburg, Sweden.
  • Nilsson O; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96, Gothenburg, Sweden.
  • Lulla A; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, United Kingdom.
  • Håversen L; Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, SE-413 45, Gothenburg, Sweden.
  • Brear P; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, United Kingdom.
  • Liljenberg S; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96, Gothenburg, Sweden.
  • Hyvönen M; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, United Kingdom.
  • Borén J; Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, SE-413 45, Gothenburg, Sweden.
  • Grøtli M; Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96, Gothenburg, Sweden. Electronic address: grotli@chem.gu.se.
Eur J Med Chem ; 250: 115177, 2023 Mar 15.
Article en En | MEDLINE | ID: mdl-36753880
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piruvato Quinasa / Hígado Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Francia
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piruvato Quinasa / Hígado Idioma: En Revista: Eur J Med Chem Año: 2023 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Francia