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A Perspective on Current Therapeutic Molecule Screening Methods Against 'Candidatus Liberibacter asiaticus', the Presumed Causative Agent of Citrus Huanglongbing.
Kennedy, John Paul; Wood, Kimberly; Pitino, Marco; Mandadi, Kranthi; Igwe, David O; Shatters, Robert G; Widmer, Timothy L; Niedz, Randall; Heck, Michelle.
Afiliación
  • Kennedy JP; U.S. Horticultural Research Laboratory, U.S. Department of Agriculture-Agricultural Research Service, Fort Pierce, FL 34945.
  • Wood K; AgroSource, Inc., Juniper, FL 33469.
  • Pitino M; AgroSource, Inc., Juniper, FL 33469.
  • Mandadi K; Department of Plant Pathology and Microbiology, Texas A&M AgriLife Research and Extension Center, Weslaco, TX 78596.
  • Igwe DO; Texas A&M AgriLife Institute for Advancing Health Through Agriculture, Texas A&M AgriLife, College Station, TX 77843.
  • Shatters RG; Plant Pathology and Plant-Microbe Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, NY 14853.
  • Widmer TL; U.S. Horticultural Research Laboratory, U.S. Department of Agriculture-Agricultural Research Service, Fort Pierce, FL 34945.
  • Niedz R; U.S. Department of Agriculture-Agricultural Research Service, Beltsville, MD 20705.
  • Heck M; U.S. Horticultural Research Laboratory, U.S. Department of Agriculture-Agricultural Research Service, Fort Pierce, FL 34945.
Phytopathology ; 113(7): 1171-1179, 2023 Jul.
Article en En | MEDLINE | ID: mdl-36750555
Huanglongbing (HLB), referred to as citrus greening disease, is a bacterial disease impacting citrus production worldwide and is fatal to young trees and mature trees of certain varieties. In some areas, the disease is devastating the citrus industry. A successful solution to HLB will be measured in economics: citrus growers need treatments that improve tree health, fruit production, and most importantly, economic yield. The profitability of citrus groves is the ultimate metric that truly matters when searching for solutions to HLB. Scientific approaches used in the laboratory, greenhouse, or field trials are critical to the discovery of those solutions and to estimate the likelihood of success of a treatment aimed at commercialization. Researchers and the citrus industry use a number of proxy evaluations of potential HLB solutions; understanding the strengths and limitations of each assay, as well as how best to compare different assays, is critical for decision-making to advance therapies into field trials and commercialization. This perspective aims to help the reader compare and understand the limitations of different proxy evaluation systems based on the treatment and evaluation under consideration. The researcher must determine the suitability of one or more of these metrics to identify treatments and predict the usefulness of these treatments in having an eventual impact on citrus production and HLB mitigation. As therapies advance to field trials in the next few years, a reevaluation of these metrics will be useful to guide future research efforts on strategies to mitigate HLB and vascular bacterial pathogens in other perennial crops.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rhizobiaceae / Citrus Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Phytopathology Asunto de la revista: BOTANICA Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Rhizobiaceae / Citrus Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Phytopathology Asunto de la revista: BOTANICA Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos