Intracranial nanomedicine-gel with deep brain-penetration for glioblastoma therapy.

Das, Devika; Narayanan, Dhanya; Ramachandran, Ranjith; Gowd, Genekehal Siddaramana; Manohar, Maneesh; Arumugam, Thennavan; Panikar, Dilip; Nair, Shantikumar V; Koyakutty, Manzoor

Das, Devika; Narayanan, Dhanya; Ramachandran, Ranjith; Gowd, Genekehal Siddaramana; Manohar, Maneesh; Arumugam, Thennavan; Panikar, Dilip; Nair, Shantikumar V; Koyakutty, Manzoor.

Afiliación

Das D; Amrita Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi, Kerala 682041, India.
Narayanan D; Amrita Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi, Kerala 682041, India.
Ramachandran R; Amrita Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi, Kerala 682041, India.
Gowd GS; Amrita Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi, Kerala 682041, India.
Manohar M; Amrita Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi, Kerala 682041, India.
Arumugam T; Central Lab Animal Facility, Amrita Vishwa Vidyapeetham, Kochi, Kerala 682041, India.
Panikar D; Amrita Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi, Kerala 682041, India.
Nair SV; Amrita Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi, Kerala 682041, India.
Koyakutty M; Amrita Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi, Kerala 682041, India. Electronic address: manzoork@acnsmm.aims.amrita.edu.

J Control Release ; 355: 474-488, 2023 03.

Article en En | MEDLINE | ID: mdl-36739909

Asunto(s)

Neoplasias Encefálicas; Glioblastoma; Glioma; Nanopartículas; Ratas; Animales; Glioblastoma/tratamiento farmacológico; Glioblastoma/metabolismo; Carmustina/uso terapéutico; Preparaciones de Acción Retardada/metabolismo; Nanomedicina; Encéfalo/metabolismo; Glioma/tratamiento farmacológico; Neoplasias Encefálicas/tratamiento farmacológico; Neoplasias Encefálicas/metabolismo; Polietilenglicoles/uso terapéutico

Palabras clave

BCNU; Brain diffusion; Drug delivery; Nanoparticle gel; PEG; PLGA; Sustained release

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Encefálicas / Glioblastoma / Nanopartículas / Glioma Límite: Animals Idioma: En Revista: J Control Release Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos

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