Toll-like receptor 4 is a key regulator of asthma exacerbation caused by aluminum oxide nanoparticles via regulation of NF-&#954;B phosphorylation.

Lim, Je-Oh; Kim, Woong-Il; Pak, So-Won; Lee, Se-Jin; Park, Sung-Hyeuk; Shin, In-Sik; Kim, Jong-Choon

Toll-like receptor 4 is a key regulator of asthma exacerbation caused by aluminum oxide nanoparticles via regulation of NF-κB phosphorylation.

Lim, Je-Oh; Kim, Woong-Il; Pak, So-Won; Lee, Se-Jin; Park, Sung-Hyeuk; Shin, In-Sik; Kim, Jong-Choon.

Afiliación

Lim JO; College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea; Herbal Medicine Resources Research Center, Korea Institute of Oriental Medicine, Naju 58245, Republic of Korea.
Kim WI; College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.
Pak SW; College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.
Lee SJ; College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.
Park SH; College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.
Shin IS; College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea.
Kim JC; College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of Korea. Electronic address: toxkim@jnu.ac.kr.

J Hazard Mater ; 448: 130884, 2023 04 15.

Article en En | MEDLINE | ID: mdl-36736217

Asunto(s)

Asma; FN-kappa B; Receptor Toll-Like 4; Animales; Humanos; Ratones; Asma/inducido químicamente; Asma/metabolismo; Líquido del Lavado Bronquioalveolar; Citocinas/metabolismo; Pulmón; Ratones Endogámicos BALB C; Factor 88 de Diferenciación Mieloide/genética; Factor 88 de Diferenciación Mieloide/metabolismo; FN-kappa B/metabolismo; Inhibidor NF-kappaB alfa/metabolismo; Inhibidor NF-kappaB alfa/farmacología; Ovalbúmina; Fosforilación; Receptor Toll-Like 4/genética; Receptor Toll-Like 4/metabolismo; Óxido de Aluminio/efectos adversos; Nanopartículas del Metal/efectos adversos

Palabras clave

Airway inflammation; Aluminum oxide nanoparticle; Asthma; Nuclear factor-kappa B; Toll-like receptor 4

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Asma / FN-kappa B / Receptor Toll-Like 4 Límite: Animals / Humans Idioma: En Revista: J Hazard Mater Asunto de la revista: SAUDE AMBIENTAL Año: 2023 Tipo del documento: Article Pais de publicación: Países Bajos

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