Development of Human Carbonic Anhydrase II Heterobifunctional Degraders.

O'Herin, Conor B; Moriuchi, Yuta W; Bemis, Troy A; Kohlbrand, Alysia J; Burkart, Michael D; Cohen, Seth M

O'Herin, Conor B; Moriuchi, Yuta W; Bemis, Troy A; Kohlbrand, Alysia J; Burkart, Michael D; Cohen, Seth M.

Afiliación

O'Herin CB; Department of Chemistry and Biochemistry, University of California, La Jolla, California 92093, United States.
Moriuchi YW; Department of Chemistry and Biochemistry, University of California, La Jolla, California 92093, United States.
Bemis TA; Department of Chemistry and Biochemistry, University of California, La Jolla, California 92093, United States.
Kohlbrand AJ; Department of Chemistry and Biochemistry, University of California, La Jolla, California 92093, United States.
Burkart MD; Department of Chemistry and Biochemistry, University of California, La Jolla, California 92093, United States.
Cohen SM; Department of Chemistry and Biochemistry, University of California, La Jolla, California 92093, United States.

J Med Chem ; 66(4): 2789-2803, 2023 02 23.

Article en En | MEDLINE | ID: mdl-36735827

Asunto(s)

Anhidrasa Carbónica II; Ubiquitina-Proteína Ligasas; Humanos; Proteolisis; Anhidrasa Carbónica II/metabolismo; Células HEK293; Ubiquitina-Proteína Ligasas/metabolismo; Proteínas/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anhidrasa Carbónica II / Ubiquitina-Proteína Ligasas Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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