Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates.

Seo, Myung-Eui; Min, Byung-Joo; Heo, Nayoon; Lee, Kye Hwa; Kim, Ju Han

Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates.

Seo, Myung-Eui; Min, Byung-Joo; Heo, Nayoon; Lee, Kye Hwa; Kim, Ju Han.

Afiliación

Seo ME; Seoul National University Biomedical Informatics (SNUBI), Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.
Min BJ; National Forensic Service Seoul Institute, Seoul, South Korea.
Heo N; Department of Mathematics, University of California, Los Angeles, Los Angeles, CA, United States.
Lee KH; Department of Information Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, South Korea.
Kim JH; Seoul National University Biomedical Informatics (SNUBI), Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, South Korea.

Front Pharmacol ; 14: 1055991, 2023.

Article en En | MEDLINE | ID: mdl-36713839

Palabras clave

CPIC guidelines; PharmGkB; PharmVar; cytochrome P450 2C19 (CYP2C19); mephenytoin; omeprazole; pharmacogenetics; pharmacogenomics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline / Prognostic_studies / Qualitative_research Idioma: En Revista: Front Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: Corea del Sur Pais de publicación: Suiza

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