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The Association Between Inflammatory Bowel Disease and Exposure to Tobacco Smoking: A Case-Control Study in Qatar.
Abdallah, Bushra; Arif, Mariah; Al-Malki, Maryam; Hourani, Razan; Al-Maadeed, Tamader; Khodr, Nidal; Al-Kuwari, Ghaith; Al-Siddiqi, Mashael; Kane, Tanya; Chivese, Tawanda.
Afiliación
  • Abdallah B; Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar.
  • Arif M; Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar.
  • Al-Malki M; Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar.
  • Hourani R; Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar.
  • Al-Maadeed T; Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar.
  • Khodr N; Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar.
  • Al-Kuwari G; Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar.
  • Al-Siddiqi M; Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar.
  • Kane T; Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar.
  • Chivese T; Department of Population Medicine, College of Medicine, QU Health, Qatar University, Doha, Qatar.
Int J Gen Med ; 16: 233-242, 2023.
Article en En | MEDLINE | ID: mdl-36711427
Objective: This research investigated the association between childhood and adulthood tobacco smoking exposure with ulcerative colitis (UC) and Crohn's disease (CD) in Qatar. Study Design and Setting: In this case-control study, CD and UC cases were matched to controls of the same age and sex. The associations between UC and CD and childhood passive smoking and adulthood active smoking were assessed using conditional multivariable logistic regression. Results: A total of 89 CD cases, median age of 37 years (IQR 29-47), and 362 UC cases, median age of 35 years (IQR 28-44), and equal numbers of controls were included. After multivariable logistic regression, CD was associated with higher odds of being a current smoker (OR 2.51, 95% CI 0.85-7.37, p=0.095), with weak evidence against the null hypothesis. This association was more pronounced in women, where CD was associated with both adulthood current smoking (OR 42.71, 95% CI, 1.17-1559.57, p=0.041), and childhood smoking exposure (OR 8.23, 95% CI, 1.36-49.66, p=0.021). In males, no associations were observed between CD and the smoking exposures. No associations were observed between UC and both smoking variables. Conclusion: In Qatar, adulthood tobacco smoking appears to increase the odds of CD. Further, our findings suggest that both childhood and adulthood cigarette smoke exposure may possibly have a detrimental effect on the odds of CD in females but not in males, although further research is needed.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: Int J Gen Med Año: 2023 Tipo del documento: Article País de afiliación: Qatar Pais de publicación: Nueva Zelanda
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: Int J Gen Med Año: 2023 Tipo del documento: Article País de afiliación: Qatar Pais de publicación: Nueva Zelanda