Your browser doesn't support javascript.
loading
Neuropsychiatric post-acute sequelae of COVID-19: prevalence, severity, and impact of vaccination.
Elmazny, Alaa; Magdy, Rehab; Hussein, Mona; Elsebaie, Eman H; Ali, Sara H; Abdel Fattah, Ali M; Hassan, Mahmoud; Yassin, Ahmed; Mahfouz, Noha A; Elsayed, Radwa M; Fathy, Wael; Abdel-Hamid, Hoda M; Abdelbadie, Mohamed; Soliman, Shaimaa H.
Afiliación
  • Elmazny A; Department of Neurology, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Magdy R; College of Medicine and Medial Science, Arabian Gulf University, Manama, Bahrain.
  • Hussein M; Department of Neurology, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Elsebaie EH; Department of Neurology, Faculty of Medicine, Beni-Suef University, Salah Salem Street, Beni Suef, 62511, Egypt. mona.neuro@yahoo.com.
  • Ali SH; Department of Public Health and Community Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Abdel Fattah AM; Department of Otolaryngology, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt.
  • Hassan M; Department of Gastroenterology, Hepatology, and Endemic Medicine, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt.
  • Yassin A; Department of Internal Medicine, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt.
  • Mahfouz NA; Department of Critical Care Medicine, Beni-Suef University, Beni Suef, Egypt.
  • Elsayed RM; Department of Psychiatry Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Fathy W; Department of Family Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Abdel-Hamid HM; Department of Anesthesiology, Surgical ICU and Pain Management, Beni-Suef University, Beni Suef, Egypt.
  • Abdelbadie M; Department of Chest Diseases, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Soliman SH; Department of Anesthesiology, Surgical ICU and Pain Management, Beni-Suef University, Beni Suef, Egypt.
Eur Arch Psychiatry Clin Neurosci ; 273(6): 1349-1358, 2023 Sep.
Article en En | MEDLINE | ID: mdl-36707454
The potential long-term neuropsychiatric effects of COVID-19 are of global concern. This study aimed to determine the prevalence and predictors of neuropsychiatric post-acute sequelae of COVID-19 among Egyptian COVID-19 survivors and to study the impact of full vaccination before COVID-19 infection on the occurrence and severity of these manifestations. Three months after getting COVID-19 infection, 1638 COVID-19 survivors were screened by phone for possible neuropsychiatric sequelae. Subjects suspected to suffer from these sequelae were invited to a face-to-face interview for objective evaluation. They were requested to rate the severity of their symptoms using visual analogue scales (VAS). The mean age of participants was 38.28 ± 13 years. Only 18.6% were fully vaccinated before COVID-19 infection. Neuropsychiatric post-acute sequelae of COVID-19 were documented in 598 (36.5%) subjects, fatigue was the most frequent one (24.6%), followed by insomnia (16.4%), depression (15.3%), and anxiety (14.4%). Moderate and severe COVID-19 infection and non-vaccination increased the odds of developing post-COVID-19 neuropsychiatric manifestations by 2 times (OR 1.95, 95% CI = 1.415-2.683), 3.86 times (OR 3.86, 95% CI = 2.358-6.329), and 1.67 times (OR 1.67, 95% CI = 1.253-2.216), respectively. Fully vaccinated subjects before COVID-19 infection (n = 304) had significantly lesser severity of post-COVID-19 fatigue, ageusia/hypogeusia, dizziness, tinnitus, and insomnia (P value = 0.001, 0.008, < 0.001, 0.025, and 0.005, respectively) than non-vaccinated subjects. This report declared neuropsychiatric sequelae in 36.5% of Egyptian COVID-19 survivors, fatigue being the most prevalent. The effectiveness of COVID-19 vaccines in reducing the severity of some post-COVID-19 neuropsychiatric manifestations may improve general vaccine acceptance.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 / Trastornos del Inicio y del Mantenimiento del Sueño Tipo de estudio: Etiology_studies / Prevalence_studies / Qualitative_research / Risk_factors_studies Límite: Adult / Humans / Middle aged Idioma: En Revista: Eur Arch Psychiatry Clin Neurosci Asunto de la revista: NEUROLOGIA / PSIQUIATRIA Año: 2023 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 / Trastornos del Inicio y del Mantenimiento del Sueño Tipo de estudio: Etiology_studies / Prevalence_studies / Qualitative_research / Risk_factors_studies Límite: Adult / Humans / Middle aged Idioma: En Revista: Eur Arch Psychiatry Clin Neurosci Asunto de la revista: NEUROLOGIA / PSIQUIATRIA Año: 2023 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Alemania