A complex equation - adding to Plasmodium falciparum invasion.

Björnsson, Kasper H; Barfod, Lea

Björnsson, Kasper H; Barfod, Lea.

Afiliación

Björnsson KH; Centre for Medical Parasitology, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Barfod L; Centre for Medical Parasitology, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. Electronic address: lbarfod@sund.ku.dk.

Trends Parasitol ; 39(3): 160-162, 2023 03.

Article en En | MEDLINE | ID: mdl-36682939

RESUMEN

The Plasmodium falciparum invasion complex - consisting of the prime blood-stage vaccine candidates PfRH5, PfCyRPA and PfRipr - is essential and conserved. New data from Scally et al. reveal that the complex consists of two additional proteins, adding important knowledge to the current understanding of the biology behind the invasion process.

Asunto(s)

Vacunas contra la Malaria; Malaria Falciparum; Humanos; Plasmodium falciparum; Proteínas Protozoarias/metabolismo; Antígenos de Protozoos/metabolismo; Proteínas Portadoras/metabolismo; Anticuerpos Antiprotozoarios; Eritrocitos; Malaria Falciparum/prevención & control

Palabras clave

PfCyRPA; PfRH5; PfRipr; Plasmodium falciparum; blood-stage vaccines; erythrocyte invasion

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malaria Falciparum / Vacunas contra la Malaria Límite: Humans Idioma: En Revista: Trends Parasitol Asunto de la revista: PARASITOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido

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