Effect of pharmacological modulation of the kynurenine pathway on pain-related behavior and opioid analgesia in a mouse model of neuropathic pain.

Ciapala, Katarzyna; Pawlik, Katarzyna; Ciechanowska, Agata; Mika, Joanna; Rojewska, Ewelina

Ciapala, Katarzyna; Pawlik, Katarzyna; Ciechanowska, Agata; Mika, Joanna; Rojewska, Ewelina.

Afiliación

Ciapala K; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pain Pharmacology, Krakow, Poland.
Pawlik K; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pain Pharmacology, Krakow, Poland.
Ciechanowska A; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pain Pharmacology, Krakow, Poland.
Mika J; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pain Pharmacology, Krakow, Poland.
Rojewska E; Maj Institute of Pharmacology, Polish Academy of Sciences, Department of Pain Pharmacology, Krakow, Poland. Electronic address: rojewska@if-pan.krakow.pl.

Toxicol Appl Pharmacol ; 461: 116382, 2023 02 15.

Article en En | MEDLINE | ID: mdl-36681127

Asunto(s)

Analgesia; Neuralgia; Ratones; Animales; Quinurenina/metabolismo; Analgésicos Opioides/farmacología; Triptófano Oxigenasa; Neuralgia/tratamiento farmacológico; ARN Mensajero/genética

Palabras clave

Indoleamine 2,3-dioxygenase (IDO); Kynurenine 3-monooxygenase (KMO); Kynurenine pathway; L-kynurenine; Neuropathic pain; Opioids

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Analgesia / Neuralgia Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Toxicol Appl Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Estados Unidos

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