TGFß1-Induced EMT in the MCF10A Mammary Epithelial Cell Line Model Is Executed Independently of SNAIL1 and ZEB1 but Relies on JUNB-Coordinated Transcriptional Regulation.

Antón-García, Pablo; Haghighi, Elham Bavafaye; Rose, Katja; Vladimirov, Georg; Boerries, Melanie; Hecht, Andreas

Antón-García, Pablo; Haghighi, Elham Bavafaye; Rose, Katja; Vladimirov, Georg; Boerries, Melanie; Hecht, Andreas.

Afiliación

Antón-García P; Institute of Molecular Medicine and Cell Research, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.
Haghighi EB; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany.
Rose K; Institute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Vladimirov G; Institute of Molecular Medicine and Cell Research, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.
Boerries M; Institute of Molecular Medicine and Cell Research, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany.
Hecht A; Institute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.

Cancers (Basel) ; 15(2)2023 Jan 16.

Article en En | MEDLINE | ID: mdl-36672507

Palabras clave

JUNB; SNAIL1; TGFß signaling; ZEB1; breast cancer; chromatin accessibility; epithelial-mesenchymal transition; invasion; metastasis; transcriptional regulation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Cancers (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza

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