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Host Microbiomes Influence the Effects of Diet on Inflammation and Cancer.
Mahmood, Ramsha; Voisin, Athalia; Olof, Hana; Khorasaniha, Reihane; Lawal, Samuel A; Armstrong, Heather K.
Afiliación
  • Mahmood R; Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.
  • Voisin A; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.
  • Olof H; Department of Immunology, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.
  • Khorasaniha R; Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.
  • Lawal SA; Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.
  • Armstrong HK; Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.
Cancers (Basel) ; 15(2)2023 Jan 14.
Article en En | MEDLINE | ID: mdl-36672469
Cancer is the second leading cause of death globally, and there is a growing appreciation for the complex involvement of diet, microbiomes, and inflammatory processes culminating in tumorigenesis. Although research has significantly improved our understanding of the various factors involved in different cancers, the underlying mechanisms through which these factors influence tumor cells and their microenvironment remain to be completely understood. In particular, interactions between the different microbiomes, specific dietary factors, and host cells mediate both local and systemic immune responses, thereby influencing inflammation and tumorigenesis. Developing an improved understanding of how different microbiomes, beyond just the colonic microbiome, can interact with dietary factors to influence inflammatory processes and tumorigenesis will support our ability to better understand the potential for microbe-altering and dietary interventions for these patients in future.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cancers (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cancers (Basel) Año: 2023 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Suiza