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Heating-mediated purification of active FGF21 and structure-based design of its variant with enhanced potency.
Jung, Ye-Eun; Lee, Kyeong Won; Cho, Jae Hyun; Bae, Da-Woon; Jeong, Bo-Gyeong; Jung, Yeon-Ju; Park, Soo-Bong; An, Young Jun; Kim, Kyungchan; Lee, Ga Seul; Kang, Lin-Woo; Moon, Jeong Hee; Lee, Jung-Hyun; Kim, Eun-Kyoung; Yim, Hyung-Soon; Cha, Sun-Shin.
Afiliación
  • Jung YE; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
  • Lee KW; Marine Biotechnology Research Center, Korea Institute of Ocean Science and Technology, 385 Haeyang-Ro, Busan, 49111, Republic of Korea.
  • Cho JH; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology, Daegu, 42988, Republic of Korea.
  • Bae DW; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
  • Jeong BG; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
  • Jung YJ; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
  • Park SB; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.
  • An YJ; Marine Biotechnology Research Center, Korea Institute of Ocean Science and Technology, 385 Haeyang-Ro, Busan, 49111, Republic of Korea.
  • Kim K; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology, Daegu, 42988, Republic of Korea.
  • Lee GS; Disease Target Structure Research Center, Korea Research Institute Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea.
  • Kang LW; Department of Biological Sciences, Konkuk University, Seoul, 05029, Republic of Korea.
  • Moon JH; Disease Target Structure Research Center, Korea Research Institute Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea.
  • Lee JH; Marine Biotechnology Research Center, Korea Institute of Ocean Science and Technology, 385 Haeyang-Ro, Busan, 49111, Republic of Korea.
  • Kim EK; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology, Daegu, 42988, Republic of Korea. ekkim@dgist.ac.kr.
  • Yim HS; Neurometabolomics Research Center, Daegu Gyeongbuk Institute of Science and Technology, Daegu, 42988, Republic of Korea. ekkim@dgist.ac.kr.
  • Cha SS; Marine Biotechnology Research Center, Korea Institute of Ocean Science and Technology, 385 Haeyang-Ro, Busan, 49111, Republic of Korea. yimh@kiost.ac.kr.
Sci Rep ; 13(1): 1005, 2023 01 18.
Article en En | MEDLINE | ID: mdl-36653390
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad del Hígado Graso no Alcohólico / Calefacción Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad del Hígado Graso no Alcohólico / Calefacción Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido