The double-stranded RNA-dependent protein kinase PKR negatively regulates the protein expression of IFN-ß induced by RIG-I signaling.

Matsumiya, Tomoh; Shiba, Yuko; Ding, Jiangli; Kawaguchi, Shogo; Seya, Kazuhiko; Imaizumi, Tadaatsu

Matsumiya, Tomoh; Shiba, Yuko; Ding, Jiangli; Kawaguchi, Shogo; Seya, Kazuhiko; Imaizumi, Tadaatsu.

Afiliación

Matsumiya T; Department of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, Hirosaki, Japan.
Shiba Y; Department of Vascular Biology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Ding J; Department of Bioscience and Laboratory Medicine, Hirosaki University Graduate School of Health Sciences, Hirosaki, Japan.
Kawaguchi S; Department of Vascular Biology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Seya K; Department of Vascular Biology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Imaizumi T; Department of Vascular Biology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.

FASEB J ; 37(2): e22780, 2023 02.

Article en En | MEDLINE | ID: mdl-36651716

Asunto(s)

ARN Bicatenario; eIF-2 Quinasa; eIF-2 Quinasa/metabolismo; Proteína 58 DEAD Box/genética; Proteína 58 DEAD Box/metabolismo; Transducción de Señal/genética; Antivirales

Palabras clave

PKR; RIG-I; antiviral signaling; innate immunity; stress granules

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Bicatenario / EIF-2 Quinasa Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

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