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The diagnostic value of staging laparoscopy in gallbladder cancer: a nationwide cohort study.
van Dooren, Mike; de Savornin Lohman, Elise A J; Brekelmans, Eva; Vissers, Pauline A J; Erdmann, Joris I; Braat, Andries E; Hagendoorn, Jeroen; Daams, Freek; van Dam, Ronald M; de Boer, Marieke T; van den Boezem, Peter B; Koerkamp, Bas Groot; de Reuver, Philip R.
Afiliación
  • van Dooren M; Department of Surgery, Radboud university medical center, P.O. Box 9101, Internal Code 618, 6500 HB, Nijmegen, the Netherlands. mike.vandooren@radboudumc.nl.
  • de Savornin Lohman EAJ; Department of Surgery, Radboud university medical center, P.O. Box 9101, Internal Code 618, 6500 HB, Nijmegen, the Netherlands.
  • Brekelmans E; Department of Surgery, Radboud university medical center, P.O. Box 9101, Internal Code 618, 6500 HB, Nijmegen, the Netherlands.
  • Vissers PAJ; Department of Research, Netherlands Comprehensive Cancer Organization (IKNL), P.O. Box 19079, 3501 DB, Utrecht, the Netherlands.
  • Erdmann JI; Department of Surgery, Amsterdam University Medical Centers, P.O. Box 22660, 1100 DD, Amsterdam, the Netherlands.
  • Braat AE; Department of Surgery, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, the Netherlands.
  • Hagendoorn J; Department of Surgery, UMC Utrecht Cancer Center, P.O. Box 85500, 3508 GA, Utrecht, the Netherlands.
  • Daams F; Department of Surgery, St. Antonius Hospital, P.O. Box 2500, 3430 EM, Nieuwegein, the Netherlands.
  • van Dam RM; Department of Surgery, Amsterdam University Medical Centers, P.O. Box 22660, 1100 DD, Amsterdam, the Netherlands.
  • de Boer MT; Department of Surgery, Maastricht University Medical Center +, P.O. Box 5800, 6202 AZ, Maastricht, the Netherlands.
  • van den Boezem PB; Department of Hepatobiliary and Transplant Surgery, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, the Netherlands.
  • Koerkamp BG; Department of Surgery, Radboud university medical center, P.O. Box 9101, Internal Code 618, 6500 HB, Nijmegen, the Netherlands.
  • de Reuver PR; Department of Surgery, Erasmus MC, P.O. Box 2060, 3000 CB, Rotterdam, the Netherlands.
World J Surg Oncol ; 21(1): 6, 2023 Jan 14.
Article en En | MEDLINE | ID: mdl-36641472
BACKGROUND: Disseminated disease (DD) is often found at (re-)exploration in gallbladder cancer (GBC) patients. We aimed to assess the yield of staging laparoscopy (SL) and identify predictors for DD. METHODS: This retrospective study included patients from all Dutch academic centres with primary GBC (pGBC) and incidentally diagnosed GBC (iGBC) planned for (re-)resection. The yield of SL was determined. In iGBC, predictive factors for DD were assessed. RESULTS: In total, 290 patients were included. Of 183 included pGBC patients, 143 underwent laparotomy without SL, and 42 (29%) showed DD perioperatively. SL, conducted in 40 patients, identified DD in eight. DD was found in nine of 32 patients who underwent laparotomy after SL. Of 107 included iGBC patients, 100 underwent laparotomy without SL, and 19 showed DD perioperatively. SL, conducted in seven patients, identified DD in one. Cholecystitis (OR = 4.25; 95% CI 1.51-11.91) and primary R1/R2 resection (OR = 3.94; 95% CI 1.39-11.19) were independent predictive factors for DD. CONCLUSIONS: In pGBC patients, SL may identify DD in up to 20% of patients and should be part of standard management. In iGBC patients, SL is indicated after primary resection for cholecystitis and after initial R1/R2 resection due to the association of these factors with DD.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma in Situ / Colecistitis / Laparoscopía / Neoplasias de la Vesícula Biliar Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: World J Surg Oncol Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma in Situ / Colecistitis / Laparoscopía / Neoplasias de la Vesícula Biliar Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: World J Surg Oncol Año: 2023 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido