Protein superglue inspired in-situ one-step site-specific immobilization of beta2-adrenoceptor and its application in bioactive compound screening from Cortex Magnoliae Officinalis.

Xue, Yan; Zhang, Zilong; Wang, Ge; Wan, Shuangru; Li, Qian; Zhao, Xinfeng

Xue, Yan; Zhang, Zilong; Wang, Ge; Wan, Shuangru; Li, Qian; Zhao, Xinfeng.

Afiliación

Xue Y; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China.
Zhang Z; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China.
Wang G; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China.
Wan S; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China.
Li Q; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China. Electronic address: 20185365@nwu.edu.cn.
Zhao X; College of Life Science, Northwest University, Xi'an, Shaanxi 710069, China.

J Chromatogr A ; 1690: 463780, 2023 Feb 08.

Article en En | MEDLINE | ID: mdl-36638688

Asunto(s)

Cromatografía; Descubrimiento de Drogas; Humanos; Unión Proteica; Ligandos; Receptores Adrenérgicos/metabolismo; Receptores Adrenérgicos beta 2/química

Palabras clave

Bioactive compound screening; One-step immobilization; Protein superglue; Spy toolbox; Β(2)-adrenoceptor

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromatografía / Descubrimiento de Drogas Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Revista: J Chromatogr A Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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