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Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity.
Shinoda, Koji; Li, Rui; Rezk, Ayman; Mexhitaj, Ina; Patterson, Kristina R; Kakara, Mihir; Zuroff, Leah; Bennett, Jeffrey L; von Büdingen, H-Christian; Carruthers, Robert; Edwards, Keith R; Fallis, Robert; Giacomini, Paul S; Greenberg, Benjamin M; Hafler, David A; Ionete, Carolina; Kaunzner, Ulrike W; Lock, Christopher B; Longbrake, Erin E; Pardo, Gabriel; Piehl, Fredrik; Weber, Martin S; Ziemssen, Tjalf; Jacobs, Dina; Gelfand, Jeffrey M; Cross, Anne H; Cameron, Briana; Musch, Bruno; Winger, Ryan C; Jia, Xiaoming; Harp, Christopher T; Herman, Ann; Bar-Or, Amit.
Afiliación
  • Shinoda K; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Li R; Center for Neuroinflammation and Experimental Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Rezk A; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Mexhitaj I; Center for Neuroinflammation and Experimental Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Patterson KR; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Kakara M; Center for Neuroinflammation and Experimental Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Zuroff L; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Bennett JL; Center for Neuroinflammation and Experimental Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • von Büdingen HC; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Carruthers R; Center for Neuroinflammation and Experimental Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Edwards KR; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Fallis R; Center for Neuroinflammation and Experimental Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Giacomini PS; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Greenberg BM; Center for Neuroinflammation and Experimental Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Hafler DA; Departments of Neurology and Ophthalmology, Programs in Neuroscience and Immunology, University of Colorado School of Medicine, Aurora, CO 80045.
  • Ionete C; F. Hoffmann-La Roche, 4070 Basel, Switzerland.
  • Kaunzner UW; Department of Medicine, University of British Columbia, Vancouver, BC V6T 2B5, Canada.
  • Lock CB; Multiple Sclerosis Center of Northeastern New York, Comprehensive MS Care Center Affiliated with the National MS Society, Latham, NY 12110.
  • Longbrake EE; Department of Neurology, Ohio State University Medical Center, Columbus, OH 43210.
  • Pardo G; Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada.
  • Piehl F; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Weber MS; Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06510.
  • Ziemssen T; Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655.
  • Jacobs D; Judith Jaffe Multiple Sclerosis Center, Weill Cornell Medicine, New York, NY 10021.
  • Gelfand JM; Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA 94304.
  • Cross AH; Department of Neurology, Yale University, New Haven, CT 06510.
  • Cameron B; Oklahoma Medical Research Foundation, Multiple Sclerosis Center of Excellence, Oklahoma City, OK 73104.
  • Musch B; Department of Clinical Neuroscience, Karolinska Institute, SE-171 76 Stockholm, Sweden.
  • Winger RC; Department of Neurology, Karolinska University Hospital, SE-171 77 Stockholm, Sweden.
  • Jia X; Neuroimmunology Unit, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institute, SE-171 77 Stockholm, Sweden.
  • Harp CT; Institute of Neuropathology, University Medical Center, 37075 Göttingen, Germany.
  • Herman A; Department of Neurology, University Medical Center, 37075 Göttingen, Germany.
  • Bar-Or A; Fraunhofer-Institute for Translational Medicine and Pharmackology ITMP, 37075 Göttingen, Germany.
Proc Natl Acad Sci U S A ; 120(3): e2207291120, 2023 01 17.
Article en En | MEDLINE | ID: mdl-36634138

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Esclerosis Múltiple Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / Esclerosis Múltiple Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2023 Tipo del documento: Article Pais de publicación: Estados Unidos