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Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity.
Nemec, Václav; Khirsariya, Prashant; Janovská, Pavlína; Moyano, Paula Martín; Maier, Lukás; Procházková, Petra; Kebková, Pavlína; Gybel', Tomás; Berger, Benedict-Tilman; Chaikuad, Apirat; Reinecke, Maria; Kuster, Bernhard; Knapp, Stefan; Bryja, Vítezslav; Paruch, Kamil.
Afiliación
  • Nemec V; Department of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, Brno, 625 00, Czech Republic.
  • Khirsariya P; International Clinical Research Centre, St. Anne's University Hospital, Pekarská 53, Brno, 656 91, Czech Republic.
  • Janovská P; Department of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, Brno, 625 00, Czech Republic.
  • Moyano PM; International Clinical Research Centre, St. Anne's University Hospital, Pekarská 53, Brno, 656 91, Czech Republic.
  • Maier L; Department of Experimental Biology, Faculty of Science, Masaryk University, Kamenice 5, Brno, 625 00, Czech Republic.
  • Procházková P; Department of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, Brno, 625 00, Czech Republic.
  • Kebková P; Department of Chemistry, Faculty of Science, Masaryk University, Kamenice 5, Brno, 625 00, Czech Republic.
  • Gybel' T; International Clinical Research Centre, St. Anne's University Hospital, Pekarská 53, Brno, 656 91, Czech Republic.
  • Berger BT; Department of Experimental Biology, Faculty of Science, Masaryk University, Kamenice 5, Brno, 625 00, Czech Republic.
  • Chaikuad A; Department of Experimental Biology, Faculty of Science, Masaryk University, Kamenice 5, Brno, 625 00, Czech Republic.
  • Reinecke M; Department of Experimental Biology, Faculty of Science, Masaryk University, Kamenice 5, Brno, 625 00, Czech Republic.
  • Kuster B; Institute for Pharmaceutical Chemistry, Structural Genomics Consortium, Johann Wolfgang Goethe-University, Max-von-Laue-Strasse 15, 60438, Frankfurt am Main, Germany.
  • Knapp S; Institute for Pharmaceutical Chemistry, Structural Genomics Consortium, Johann Wolfgang Goethe-University, Max-von-Laue-Strasse 15, 60438, Frankfurt am Main, Germany.
  • Bryja V; Chair of Proteomics and Bioanalytics, TUM School of Life Sciences, Technical University of Munich, 85354, Freising, Germany.
  • Paruch K; Chair of Proteomics and Bioanalytics, TUM School of Life Sciences, Technical University of Munich, 85354, Freising, Germany.
Angew Chem Int Ed Engl ; 62(11): e202217532, 2023 03 06.
Article en En | MEDLINE | ID: mdl-36625768
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Quinasa de la Caseína I Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2023 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Quinasa de la Caseína I Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2023 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Alemania