Angiotensin-(1-7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-&#954;B and MAPK pathways.

Chen, Xin-Sen; Cui, Jing-Rui; Meng, Xiang-Long; Wang, Shu-Hang; Wei, Wei; Gao, Yu-Lei; Shou, Song-Tao; Liu, Yan-Cun; Chai, Yan-Fen

Angiotensin-(1-7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways.

Chen, Xin-Sen; Cui, Jing-Rui; Meng, Xiang-Long; Wang, Shu-Hang; Wei, Wei; Gao, Yu-Lei; Shou, Song-Tao; Liu, Yan-Cun; Chai, Yan-Fen.

Afiliación

Chen XS; Department of Emergency Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Cui JR; Department of Emergency Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Meng XL; Department of Emergency Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Wang SH; Department of Emergency Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Wei W; Department of Emergency Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Gao YL; Department of Emergency Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Shou ST; Department of Emergency Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China.
Liu YC; Department of Emergency Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China. yancunliu@tmu.edu.cn.
Chai YF; Department of Emergency Medicine, Tianjin Medical University General Hospital, 154 Anshan Road, Tianjin, 300052, China. chaiyanfen2012@126.com.

J Transl Med ; 21(1): 2, 2023 01 02.

Article en En | MEDLINE | ID: mdl-36593471

Asunto(s)

Cardiomiopatías; Sepsis; Humanos; FN-kappa B/metabolismo; Proteínas Quinasas Activadas por Mitógenos; Células Cultivadas; Angiotensina II/metabolismo; Cardiomiopatías/tratamiento farmacológico; Cardiomiopatías/etiología; Sepsis/complicaciones; Sepsis/tratamiento farmacológico

Palabras clave

Angiotensin (17); Angiotensin II; Apoptosis; Mitochondria; Oxidative stress; Sepsis-induced cardiomyopathy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Sepsis / Cardiomiopatías Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: J Transl Med Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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