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Severe and Moderate Primary Graft Dysfunction in Adult Heart Recipients.
Stefen, Samuel Padovani; Tenório, Davi Freitas; Cirillo, Guilherme Carvalhal Gnipper; Gaspar, Shirlyne Fabianni; Oliveira, Karen Amanda Soares de; Gaiotto, Fábio Antonio; Jatene, Fabio B.
Afiliación
  • Stefen SP; Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (InCor-HCFMUSP), São Paulo, São Paulo, Brazil.
  • Tenório DF; Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (InCor-HCFMUSP), São Paulo, São Paulo, Brazil.
  • Cirillo GCG; Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (InCor-HCFMUSP), São Paulo, São Paulo, Brazil.
  • Gaspar SF; Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (InCor-HCFMUSP), São Paulo, São Paulo, Brazil.
  • Oliveira KAS; Cardiac Surgery Department, Faculdade de Medicina, Universidade Federal de Goiás (FMUFG), Goiânia, Goiás, Brazil.
  • Gaiotto FA; Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (InCor-HCFMUSP), São Paulo, São Paulo, Brazil.
  • Jatene FB; Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (InCor-HCFMUSP), São Paulo, São Paulo, Brazil.
Braz J Cardiovasc Surg ; 38(2): 214-218, 2023 04 23.
Article en En | MEDLINE | ID: mdl-36592073
INTRODUCTION: The aims of this study were to determine the incidence of severe and moderate primary graft dysfunction (PGD) in our center, to identify, retrospectively, donors' and recipients' risk factors for PGD development, and to evaluate the impact of PGD within 30 days after heart transplantation. METHODS: Donors' and recipients' medical records of 64 consecutive adult cardiac transplantations performed between January 2016 and June 2017 were reviewed. The International Society for Heart and Lung Transplantation (ISHLT) criteria were used to diagnose moderate and severe PGD. Associations of risk factors for combined moderate/severe PGD were assessed with appropriate statistical analyses. RESULTS: Sixty-four patients underwent heart transplantation in this period. Twelve recipients (18.7%) developed severe or moderate PGD. Development of PGD was associated with previous donor cardiopulmonary resuscitation and a history of prior heart surgery in the recipient (P=0.01 and P=0.02, respectively). The 30-day in hospital mortality was similar in both PGD and non-PGD patients. CONCLUSION: The use of the ISHLT criteria for PGD is important to identify potential risk factor. The development of PGD did not affect short-term survival in our study. More studies should be done to better understand the pathophysiology of PGD.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Corazón-Pulmón / Trasplante de Corazón / Disfunción Primaria del Injerto Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Humans Idioma: En Revista: Braz J Cardiovasc Surg Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trasplante de Corazón-Pulmón / Trasplante de Corazón / Disfunción Primaria del Injerto Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Humans Idioma: En Revista: Braz J Cardiovasc Surg Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil